280761-97-9

Basic information

• Product Name: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one
• Synonyms: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one;9-Boc-3-Oxa-9-azabicyclo[3.3.1]nonan-7-one;9-Boc-3-Oxa-9-azabicyclo[...;tert-Butyl 7-oxo-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate;tert-butyl (1S,5R)-7-oxo-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate;280761-97-9
• CAS NO: 280761-97-9
• Molecular Formula: C₁₂H₁₉NO₄
• Molecular Weight: 241
• Mol File: 280761-97-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 356.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.168±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -1.86±0.20(Predicted)
• CAS DataBase Reference: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one(280761-97-9)
• EPA Substance Registry System: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one(280761-97-9)

Safety Data

• Hazardous Substances Data: 280761-97-9(Hazardous Substances Data)

Usage

General Description

9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one is a chemical compound that belongs to the class of bicyclic compounds. It is also known by its systematic IUPAC name, which describes its specific chemical structure. 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one is often used as a building block in organic synthesis and medicinal chemistry, where it can be utilized to create various other compounds with specific properties and functions. Its structural features make it a versatile and valuable intermediate in the synthesis of pharmaceuticals and other biologically active molecules. Additionally, its use in chemical research and drug development makes it an important compound in the field of organic chemistry.

Upstream product

• 1126795-00-3 3-oxa-9-azabicyclo[3.3.1]nonan-7-one hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 81514-40-1 N-benzyl-7-oxa-9-azabicyclo<3.3.1>nonan-3-one 
• 926658-87-9 3-oxa-9-azabicyclo[3.3.1]nonan-7-one 

Downstream Products

• 1126795-00-3 3-oxa-9-azabicyclo[3.3.1]nonan-7-one hydrochloride 
• 1148006-31-8 (1R,5S,7S)-tert-butyl 7-hydroxy-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate 
• 1361297-75-7 5-(3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)-3-(6-phenylpyridin-3-yl)-8,9-dihydropyrazolo[1,5-a]pyrido[3,2-e]pyrimidin-6(7H)-one 
• 1319256-94-4 tert-butyl 7-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-6-(1-ethoxyvinyl)-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yI)-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate 
• 1319256-93-3 tert-butyl 7-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-6-bromo-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate 
• 1319256-92-2 tert-butyl 7-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-3-oxa-9-azabicyclo[3.3.1]nonane-9-carboxylate 
• 1313034-29-5 tert-butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-oxa-9-azabicyclo[3 .3.1]non-6-ene-9-carboxylate 

Relevant articles and documents

SUBSTITUENT-INCLUDING UREA COMPOUND

An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases. The present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. (Each symbol in Formula (1) has the same definition as that described in the specification.)

3-OXA-8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AND THIER USE IN THE TREATMENT OF CANCER AND HEMOGLOBINOPATHIES

A compound of formula Ia, Ib, Ic or Id: wherein: n is 1 or 2;R N is H or Me; R1 is optionally one or more halo or methyl groups;R2a and R2b are independently selected from the group consisting of: (i) F; (ii) H;(iii) Me; and (iv) CH2 OH; R 2c and R 2d (if present) are independently selected from the group consisting of: (i) F; (ii) H;(iii) Me; and(iv) CH 2 OH;R 3a and R 3b are independently selected from H and Me; R 4a is selected from OH,-NH 2, -C(=O)NH 2, and -CH 2 OH; R 4b is either H or Me; R5 is either H or Me; m is 1 or 2; q is 0 or 1;R 11a, R 11b, R 11c and R 11d are independently selected from H, halo, C1-4 alkyl, C 1-4 fluoroalkyl, C 3-4 cycloalkyl, C 1-4 alkyloxy, NH-C 1-4 alkyl and cyano; R 12a and R 12b are independently selected from the group consisting of: (i) F; (ii) H;(iii) Me; and (iv) CH 2 OH; R 12c and R 12d are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH;R 12e is H or Me; R 13a and R 13b are independently selected from H and Me; R 14 is either H or Me; R 16a and R 16b are independently selected from H and Me; R 6 is selected from H, OMe, and OEt.