280784-30-7Relevant academic research and scientific papers
Ethylzincation of monosubstituted alken es catalyzed by EtMgBr-Cl2ZrCp2 and palladium-catalyzed cross coupling of the resultant diisoalkylzinc derivatives
Gagneur, Sebastien,Jean-Luc, Montchamp,Ei-ichi, Negishi
, p. 2417 - 2419 (2000)
The reaction of monosubstituted alkenes with 0.5 molar equiv of EtZn in the presence of a catalyst generated in situ by treatment ofClzZrCpz with 2 molar equiv of EtMgBr produces regioselectively the corresponding diisoalkylzincs 1, generally in high yields. Their direct cross coupling with a variety of organic halides in the same reaction vessel can be achieved in good yields with a catalytic amount of a palladium complex.
