28090-15-5

Basic information

• Product Name: 4-[(3-methylbut-2-en-1-yl)oxy]benzoic acid
• Synonyms: benzoic acid, 4-[(3-methyl-2-buten-1-yl)oxy]-
• CAS NO: 28090-15-5
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.2378
• Mol File: 28090-15-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 344°C at 760 mmHg
• Flash Point: 130.8°C
• Density: 1.112g/cm³
• Vapor Pressure: 2.58E-05mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 4-[(3-methylbut-2-en-1-yl)oxy]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3-methylbut-2-en-1-yl)oxy]benzoic acid(28090-15-5)
• EPA Substance Registry System: 4-[(3-methylbut-2-en-1-yl)oxy]benzoic acid(28090-15-5)

Safety Data

• Hazardous Substances Data: 28090-15-5(Hazardous Substances Data)

Upstream product

• 34593-50-5 methyl 4-((3-methylbut-2-en-1-yl)oxy)benzoate 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 870-63-3 prenyl bromide 
• 120-47-8 Ethyl 4-hydroxybenzoate 

Downstream Products

• 183583-83-7 N-(1,2-diethyl-4-pyrazolidinyl)-4-(3-methyl-2-butenyloxy) benzamide 
• 213998-14-2 1-ethyl-2-(4-prenyloxybenzoylaminomethyl)pyrrolidine 

Relevant articles and documents

2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate mycobacterium tuberculosis in replicating and non-replicating forms

The high mortality rate and the increasing prevalence of Mtb resistance are the major concerns for the Tuberculosis (TB) treatment in this century. To counteract the prevalence of Mtb resistance, we have synthesized 2-aryl benzazole based dual targeted molecules. Compound 9m and 9n were found to be equally active against replicating and non-replicating form of Mtb (MIC(MABA) 1.98 and 1.66 μg/ml; MIC(LORA) 2.06 and 1.59 μg/ml respectively). They arrested the cell division (replicating Mtb) by inhibiting the GTPase activity of FtsZ with IC50 values 45 and 64 μM respectively. They were also capable of kill Mtb in non-replicating form by inhibiting the biosynthesis of menaquinone which was substantiated by the MenG inhibition (IC50 = 11.62 and 7.49 μM respectively) followed by the Vit-K2 rescue study and ATP production assay.

In vitro inhibitory activity of boropinic acid against Helicobacter pylori

In this study, we assessed in vitro minimum inhibitory concentration (MIC) values of some natural geranyloxycoumarins, geranyloxy- and isopentenyloxy acids against growth of Helicobacter pylori. Boropinic acid, active principle isolated from Boronia pinnata (Fam. Rutaceae), was seen to be the most effective compound with a MIC value of 1.62 μg/mL.

Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug

An alkylenediamine derivative or a salt thereof expressed by the following formula 1: STR1 wherein each of R1 and R2 represents a lower alkyl group, and W represents a group expressed by any of the following formulas 2 and 3; STR2 wh