2815-37-4Relevant academic research and scientific papers
Isomerization of Aziridines to Allyl Amines via Titanium and Chromium Cooperative Catalysis
Yao, Chengbo,Williams, Alana D. N.,Gu, Yiting,Norton, Jack R.
, p. 4991 - 4997 (2022/04/07)
A Ti/Cr cooperative catalyst isomerizes aziridines to allyl amines under mild conditions. The reaction tolerates a broad range of aziridines with various nitrogen substituents. The titanium catalyst is most successful in opening 1,2-disubstituted aziridines, forming radical intermediates in a highly regioselective manner. The chromium catalyst appears to abstract an H? from these radical intermediates and then return the H? to the titanium system in the form of an H+ and an electron. The reaction is complementary to previous reports on the isomerization of aziridines to allyl amines.
Revisiting the Corey-Chaykovsky reaction: The solvent effect and the formation of β-hydroxy methylthioethers
Peng, Yu,Yang, Jin-Hui,Li, Wei-Dong Z.
, p. 1209 - 1215 (2007/10/03)
The classical Corey-Chaykovsky (CC) reaction of ketones in ethereal solvents (i.e., THF or Et2O) resulted in the production of a significant amount of β-hydroxy methylthioether 2 along with normal epoxide product 1. Some interesting and synthet
SULFUR YLIDES IN REACTIONS WITH 4-SUBSTITUTED CYCLOHEXANONES: STEREOCHEMISTRY AND REACTIVITY
Migneco, Luisa M.,Vecchi, Elisabetta
, p. 19 - 24 (2007/10/03)
The stereochemistry of the epoxidation reactions of the title compounds (R= Me, Et, t-Bu, Ph, p-F-Ph, OMe, OH, CF3, OCOPh) with sulfur ylides (dimethylsulfonium methylide and dimethyloxosulfonium methylide) has been determined in three different solvents (DMSO, C6H6 and THF).Relative rates have been measured and the kinetic constants kcis and ktrans determined.
Reaction of diphenylsulfonium methylide with carbonyl compounds in non-basic media
Hioki,Tani,Sato
, p. 649 - 650 (2007/10/02)
Diphenylsulfonium methylide was formed by fluoride-induced desilylation of diphenyl[(trimethylsilyl)methyl]sulfonium triflate with cesium fluoride in dimethyl sulfoxide and allowed to react with carbonyl compounds in situ to give oxiranes.
Ylide Reactions in the Solid State: a Simple Procedure for the Synthesis of Cyclopropanes, Oxiranes and Aziridines
Toda, Fumio,Imai, Nobuhiro
, p. 2673 - 2674 (2007/10/02)
Treatment of chalcones, cyclohexanones and imines with trimethyloxosulfonium or trimethylsulfonium iodide and KOH in the solid state give cyclopropanes, oxiranes and aziridines, respecively, in good yields.Solid-state methylene transfer also occurs enanti
