2815-37-4

Basic information

• Product Name: 6-phenyl-1-oxaspiro[2.5]octane
• Synonyms: 6-phenyl-1-oxaspiro[2.5]octane
• CAS NO: 2815-37-4
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 188.26554
• Mol File: 2815-37-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-phenyl-1-oxaspiro[2.5]octane(CAS DataBase Reference)
• NIST Chemistry Reference: 6-phenyl-1-oxaspiro[2.5]octane(2815-37-4)
• EPA Substance Registry System: 6-phenyl-1-oxaspiro[2.5]octane(2815-37-4)

Safety Data

• Hazardous Substances Data: 2815-37-4(Hazardous Substances Data)

Upstream product

• 6814-64-8 methylenedimethyl sulfurane 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 1774-47-6 trimethylsulfoxonium iodide 
• 2181-42-2 trimethylsulphonium iodide 

Downstream Products

• 29074-53-1 (1R,4R)-1-methyl-4-phenylcyclohexanol 
• 2862-92-2 (1S,4S)-1-methyl-4-phenylcyclohexanol 

Relevant articles and documents

Isomerization of Aziridines to Allyl Amines via Titanium and Chromium Cooperative Catalysis

A Ti/Cr cooperative catalyst isomerizes aziridines to allyl amines under mild conditions. The reaction tolerates a broad range of aziridines with various nitrogen substituents. The titanium catalyst is most successful in opening 1,2-disubstituted aziridines, forming radical intermediates in a highly regioselective manner. The chromium catalyst appears to abstract an H? from these radical intermediates and then return the H? to the titanium system in the form of an H+ and an electron. The reaction is complementary to previous reports on the isomerization of aziridines to allyl amines.

SULFUR YLIDES IN REACTIONS WITH 4-SUBSTITUTED CYCLOHEXANONES: STEREOCHEMISTRY AND REACTIVITY

The stereochemistry of the epoxidation reactions of the title compounds (R= Me, Et, t-Bu, Ph, p-F-Ph, OMe, OH, CF3, OCOPh) with sulfur ylides (dimethylsulfonium methylide and dimethyloxosulfonium methylide) has been determined in three different solvents (DMSO, C6H6 and THF).Relative rates have been measured and the kinetic constants kcis and ktrans determined.

Ylide Reactions in the Solid State: a Simple Procedure for the Synthesis of Cyclopropanes, Oxiranes and Aziridines

Treatment of chalcones, cyclohexanones and imines with trimethyloxosulfonium or trimethylsulfonium iodide and KOH in the solid state give cyclopropanes, oxiranes and aziridines, respecively, in good yields.Solid-state methylene transfer also occurs enanti