28164-35-4Relevant academic research and scientific papers
Cycloisomerization of acetylenic oximes and hydrazones under gold catalysis: Synthesis and cytotoxic evaluation of isoxazoles and pyrazoles
Jeyaveeran,Praveen, Chandrasekar,Arun,M Prince,Perumal
, p. 73 - 83 (2016/02/09)
The synthesis of substituted isoxazoles and pyrazoles through a general cycloisomerization methodology has been reported. The capability of gold(III) chloride to promote cycloisomerization of both α, β-acetylenic oximes and α, β-acetylenic hydrazones is t
Cyclometallated gold(III) complexes as effective catalysts for synthesis of propargylic amines, chiral allenes and isoxazoles
Kung, Karen Ka-Yan,Lo, Vanessa Kar-Yan,Ko, Hok-Ming,Li, Gai-Li,Chan, Pui-Ying,Leung, King-Chi,Zhou, Zhongyuan,Wang, Ming-Zhong,Che, Chi-Ming,Wong, Man-Kin
supporting information, p. 2055 - 2070 (2013/08/23)
A series of cyclometallated gold(III) complexes [Au(CN)Cl2] 1a-l (HCN=arylpyridines) and a PEG-linked complex 1m were synthesized. Complexes 1a-m are effective in catalyzing the synthesis of propargylic amines, chiral allenes and isoxazoles. Six-membered ring cyclometallated gold(III) complexes 1f-l exhibited higher catalytic activity than five-membered ring cyclometallated gold(III) complexes 1a-e. The diastereoselectivity of propargylic amines could be tuned by using chiral aldehyde and/or amine substrates. Excellent enantioselectivities (90-98% ee) were achieved in chiral allene synthesis. Chiral allene racemization could be minimized by using 1f as catalyst. The PEG-linked catalyst 1m is the most catalytically active towards synthesis of propargylic amines, in which case a product turnover of 900 was achieved. Moreover, 1m could be repeatedly used for 12 reaction cycles, leading to an overall turnover number of 872. Copyright
Gold(III)-catalyzed synthesis of isoxazoles by cycloisomerization of α,β-acetylenic oximes
Praveen,Kalyanasundaram,Perumal
body text, p. 777 - 781 (2010/06/12)
Cycloisomerization of,-acetylenic oximes leading to substituted isoxazoles was achieved using AuCl3 as catalyst, under moderate reaction conditions. The reaction can be applied to various acetylenic oximes and gives good to excellent yields. Th
Synthesis of isochalcogenazole rings by treating β-(N,N- dimethylcarbamoylchalcogenenyl)alkenyl ketones with hydroxylamine-O-sulfonic acid
Shimada, Kazuaki,Moro-oka, Akiko,Maruyama, Akiko,Fujisawa, Hiroyuki,Saito, Toshio,Kawamura, Ryo,Kogawa, Hisashi,Sakuraba, Maiko,Takata, Yukichi,Aoyagi, Shigenobu,Takikawa, Yuji,Kabuto, Chizuko
, p. 567 - 577 (2008/02/11)
β-(N,N-Dimethylcarbamoylselenenyl)- and β-(N,N- dimethylcarbamoyltellurenyl)alkenyl ketones were converted into isoselenazoles and isotellurazole Te-oxides, respectively, simply by treating with hydroxylamine-O-sulfonic acid, and deoxygenation of the latt
