28164-57-0 Usage
Uses
Used in Pharmaceutical Industry:
Diospyrin is used as a lead compound for the development of new pharmaceuticals due to its diverse biological activities, including anti-cancer, anti-inflammatory, anti-microbial, and anti-oxidant properties. Its multifaceted therapeutic potential makes it a valuable asset in the creation of novel treatments for various diseases.
Used in Cancer Therapy:
Diospyrin is utilized as an anti-cancer agent, specifically for its ability to induce cell cycle arrest and apoptosis in tumor cells. This property positions diospyrin as a promising candidate for the treatment of various types of cancer.
Used in Anti-Inflammatory Applications:
Diospyrin serves as an anti-inflammatory agent, believed to exert its effects through the inhibition of pro-inflammatory pathways. This makes it a potential therapeutic option for conditions characterized by inflammation.
Used in Antimicrobial Treatments:
Given its anti-microbial properties, diospyrin is applied in the development of treatments aimed at combating microbial infections, offering an alternative or adjunct to existing antimicrobial therapies.
Used in Antioxidant Formulations:
Leveraging its anti-oxidant capabilities, diospyrin is used in the formulation of products designed to protect against oxidative stress and related conditions, contributing to overall health and wellness.
Check Digit Verification of cas no
The CAS Registry Mumber 28164-57-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,6 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28164-57:
(7*2)+(6*8)+(5*1)+(4*6)+(3*4)+(2*5)+(1*7)=120
120 % 10 = 0
So 28164-57-0 is a valid CAS Registry Number.
28164-57-0Relevant academic research and scientific papers
Yoshida, Masao,Mori, Kenji
, p. 1313 - 1317 (2000)
The first synthesis of diospyrin [2,6'-bis(5-hydroxy-7-methyl-1,4- naphthoquinone), 1] was achieved by employing Suzuki coupling between 5 and 14 as the key reaction to connect the two 7-methyljuglone units.
Total Synthesis of the Antitumor-Antitubercular 2,6′-Bijuglone Natural Product Diospyrin and Its 3,6′-Isomer
Pullella, Glenn A.,Vuong, Daniel,Lacey, Ernest,Piggott, Matthew J.
supporting information, p. 3623 - 3634 (2021/01/09)
The 2,6′-bijuglone natural product diospyrin and its unnatural 3,6′-isomer idospyrin have been synthesized in seven steps each from N,N-diethylsenecioamide in overall yields of 12% and 13%, respectively. The syntheses diverge from ramentaceone (7-methylju
Ebenaceae Extractives. Part 8. The Structure of Diosquinone and Reactions of Related Quinone Epoxides
Lillie, Terence J.,Musgrave, Oliver C.
, p. 1161 - 1164 (2007/10/02)
Diosquinone, from Diospyros tricolor, is shown to be the naphthoquinonylnaphthoquinone epoxide (2).Juglone epoxides react with chloroform and with ethanol with the formation of chloro- and chlorohydroxy-juglones and of ethoxy- and ethoxyhydroxy-juglones respectively.
