28170-77-6Relevant academic research and scientific papers
Cu(II)-Catalyzed Ortho-C-H Nitration of Aryl Ureas by C-H Functionalization
Wang, Chun-Meng,Tang, Kai-Xiang,Gao, Tian-Hong,Chen, Lin,Sun, Li-Ping
, p. 8315 - 8321 (2018)
A novel protocol for the aromatic ortho C-H nitration of aryl ureas with Fe(NO3)3·9H2O is developed. The reaction utilizes CuCl2·2H2O as catalyst and p-TSA as additive, showing good functional group tolerance and furnishing the desired products in moderate to excellent yields.
Regioselective bromination of aryl ureas with Phenyliodine(III) diacetate and potassium bromide
Wang, Chun-Meng,Du, Jian-Yao,Zhang, Jin-Yang,Tang, Kai-Xiang,Gao, Tian-Hong,Xu, Yun-Gen,Sun, Li-Ping
, (2019/10/02)
An efficient regioselective and operationally simple urea bromination method utilizing PIDA and potassium bromide is reported. This protocol proved to be effective on a broad range of substituted ureas in acetone at room temperature, forming the p-brominated compounds in 44–86% yields.
