2818-70-4

Basic information

• Product Name: 5-IODO-2-METHYLBENZIMIDAZOLE
• Synonyms: 5-IODO-2-METHYLBENZIMIDAZOLE;5-Iodo-2-methyl-1H-benzimidazole;5-iodo-2-Methyl-1H-benzo[d]iMidazole;1H-Benzimidazole,6-iodo-2-methyl-
• CAS NO: 2818-70-4
• Molecular Formula: C₈H₇IN₂
• Molecular Weight: 258.06
• Mol File: 2818-70-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 220 °C
• Boiling Point: 419.4±18.0 °C(Predicted)
• Appearance: /
• Density: 1.933±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 10.65±0.10(Predicted)
• CAS DataBase Reference: 5-IODO-2-METHYLBENZIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-IODO-2-METHYLBENZIMIDAZOLE(2818-70-4)
• EPA Substance Registry System: 5-IODO-2-METHYLBENZIMIDAZOLE(2818-70-4)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 2818-70-4(Hazardous Substances Data)

Usage

General Description

5-IODO-2-METHYLBENZIMIDAZOLE is a chemical compound with the molecular formula C8H7IN2. It is a white to yellow crystalline powder that is primarily used as an intermediate in the synthesis of pharmaceuticals and veterinary drugs. 5-IODO-2-METHYLBENZIMIDAZOLE is known for its potential antimicrobial and antifungal properties, making it a valuable ingredient in the development of medical treatments. Additionally, 5-IODO-2-METHYLBENZIMIDAZOLE is also used in the manufacturing of agrochemicals and dyes. Its versatile properties and wide range of applications make it an important compound in the chemical industry.

Upstream product

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Relevant articles and documents

Exploring the Strength of the H-Bond in Synthetic Models for Heme Proteins: The Importance of the N?H Acidity of the Distal Base

The distal hydrogen bond (H-bond) in dioxygen-binding proteins is crucial for the discrimination of O2with respect to CO or NO. We report the preparation and characterization of a series of ZnIIporphyrins, with one of three meso-phenyl rings bearing both an alkyl-tethered proximal imidazole ligand and a heterocyclic distal H-bond donor connected by a rigid acetylene spacer. Previously, we had validated the corresponding CoIIcomplexes as synthetic model systems for dioxygen-binding heme proteins and demonstrated the structural requirements for proper distal H-bonding to CoII-bound dioxygen. Here, we systematically vary the H-bond donor ability of the distal heterocycles, as predicted based on pKavalues. The H-bond in the dioxygen adducts of the CoIIporphyrins was directly measured by Q-band Davies-ENDOR spectroscopy. It was shown that the strength of the hyperfine coupling between the dioxygen radical and the distal H-atom increases with enhanced acidity of the H-bond donor.