282089-62-7Relevant academic research and scientific papers
Synthesis and in vitro biological evaluation of carbon-11-labeled quinoline derivatives as new candidate PET radioligands for cannabinoid CB2 receptor imaging
Gao, Mingzhang,Wang, Min,Miller, Kathy D.,Hutchins, Gary D.,Zheng, Qi-Huang
experimental part, p. 2099 - 2106 (2010/06/12)
Cannabinoids have been recently proposed as a new family of potential antitumor agents, and cannabinoid receptor 2 (CB2) is believed to be over-expressed in tumor cells. This study was designed to develop new radioligands for imaging of CB2 receptor in ca
2-oxoquinoline compounds and medicinal uses thereof
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, (2008/06/13)
A 2-oxoquinoline compound or its pharmaceutically acceptable salt of general formula [I]: ? (wherein each symbol in the formula is as determined in the description), and its pharmaceutical use. The compound [I] of the present invention and its pharmaceutically acceptable salts selectively act on cannabinoid receptors, particularly on peripheral type cannabinoid receptors, and have fewer side effects on the central nervous system, having great immunosuppressive action, anti-inflammatory action or antiallergic action. Therefore, these compounds are useful as cannabinoid receptors (particularly peripheral type cannabinoid receptors) modulator, immunosuppressants, anti-inflammatory agents, and antiallergic agents.
