282095-68-5Relevant academic research and scientific papers
Asymmetric synthesis of novel spirocycles via a chiral phosphoric acid catalyzed desymmetrization
Kelley, Amber M.,Minerali, Eni,Wilent, Jennifer E.,Chambers, Nicholas J.,Stingley, Kyla J.,Wilson, G. Tyler,Petersen, Kimberly S.
, p. 1262 - 1264 (2019)
A straightforward method for the asymmetric preparation of novel lactone and lactam spirocycles is described. An initial desymmetrization via a chiral Br?nsted acid yields enantioenriched lactones which readily undergo a second cyclization to give the des
