282097-80-7

Upstream product

• 994-30-9 triethylsilyl chloride 
• 282097-88-5 (R)-4-Benzyl-3-(2-hydroxy-acetyl)-oxazolidin-2-one 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 118949-49-8 4-benzyl-3-[2-(4-methoxy-benzyloxy)-acetyl]-oxazolidin-2-one 

Downstream Products

• 282097-81-8 (R)-4-benzyl-3-[(S)-5-iodo-2-triethylsilanoxy-4-hexenoyl]oxazolidin-2-one 
• 477717-05-8 4-(R)-benzyl-3-[6,6,6-trifluoro-5-iodo-2-(S)-(triethyl-silanyloxy)-hex-4-enoyl]-oxazolidin-2-one 
• 666739-69-1 (R)-4-Benzyl-3-((E)-(S)-2-triethylsilanyloxy-5-trifluoromethyl-octa-4,7-dienoyl)-oxazolidin-2-one 
• 1055723-37-9 (R)-4-Benzyl-3-((E)-2-triethylsilanyloxy-5-trifluoromethyl-octa-4,7-dienoyl)-oxazolidin-2-one 
• 637003-64-6 (R)-4-Benzyl-3-((E)-(S)-2-hydroxy-5-trifluoromethyl-octa-4,7-dienoyl)-oxazolidin-2-one 

Relevant academic research and scientific papers

Insights into long-range structural effects on the stereochemistry of aldol condensations: A practical total synthesis of desoxyepothilone F

A processable total synthesis of a potent antitumor agent, desoxyepothilone F (dEpoF, 21-hydroxy-12,13-desoxyepothilone B, 21-hydroxyepothilone D), has been accomplished. The route is highly convergent. The new technology has also been applied to a total

En route to a plant scale synthesis of the promising antitumor agent 12,13-desoxyepothilone B.

[reaction--see text] Efficient and processable syntheses of key building blocks of the antitumor agent 12,13-desoxyepothilone B (dEpoB) by catalytic asymmetric induction are herein described.