28221-34-3Relevant academic research and scientific papers
Mechanistic Studies on Thiazolidine Formation in Aldehyde/Cysteamine Model Systems
Huang, Tzou-Chi,Huang, Lee-Zen,Ho, Chi-Tang
, p. 224 - 227 (2007/10/03)
A mechanism was proposed to elucidate the formation of a thiazolidine in aldehyde/cysteamine model systems. Buffer dramatically promotes thiazolidine formation from formaldehyde and cysteamine. Phosphate tends to stabilize the primary carbocation formed, and this may lead to completion of the cyclization by attack of the amino nitrogen on the activated carbon. Protic solvent, by removing the water molecule, further enhances thiazolidine formation. Redox reaction catalyzed by phosphate ions results in the conversion of thiazolidine to the corresponding thiazoline through hydride transfer.
Research on radioprotective agents: Δ-2 Thiazolines and homologous derivatives
Robbe,Fernandez,Chapat,et al.
, p. 16 - 24 (2007/10/02)
Compounds derived from Δ-2 thiazoline, Δ-2 thiazolinium iodoalkylate and 4,5-dihydro-1,3 thiazine have been prepared and evaluated as potential antiradiation agents in mice. They generally have a low toxicity and significant radioprotective activity.
