28228-81-1

Upstream product

• 90-96-0 bis(p-methoxyphenyl)methanone 
• 14114-05-7 cyclopropyltriphenylphosphonium bromide 
• 7333-63-3 4-bromobutylphosphonium bromide 
• 3607-17-8 3-bromopropyltriphenylphosphonium bromide 

Downstream Products

• 7035-48-5 4,4-bis(4-methoxyphenyl)-1-chlorobut-3-ene 
• 585531-37-9 1-chloro-2,2-bis(4-methoxyphenyl)-1-methylspiro[2.2]pentane 
• 111448-46-5 1-[4-bromo-1-(4-methoxyphenyl)but-1-en-1-yl]-4-methoxybenzene 
• 698389-62-7 2,4-diiodo-1,1-bis(4-methoxyphenyl)but-1-ene 
• 41635-75-0 4,4'-(buta-1,3-diene-1,1-diyl)bis(methoxybenzene) 

Relevant academic research and scientific papers

Transition Metal-Free Difunctionalization of C?C Bond with Sodium Sulfinates and Water Leading to (E)-1-Phenyl-4-sulfonylbut-1-enes

Without using any transitionmetal and base, an eco-friendly, practical and economical protocol has been established for the one-pot synthesis of diverse (E)-1-phenyl-4-sulfonylbut-1-enes from easily accessible starting materials. This strategy features a wide substrate scope, tolerates a broad range of functional groups, employs a less expensive oxidant, is operationally simple, and can be easily scaled-up. (Figure presented.).

Visible-Light-Catalyzed C-C Bond Difunctionalization of Methylenecyclopropanes with Sulfonyl Chlorides for the Synthesis of 3-Sulfonyl-1,2-dihydronaphthalenes

A novel visible-light-catalyzed sulfonylation/arylation of carbon-carbon σ-bond with sulfonyl chlorides for the synthesis of 3-sulfonylated 1,2-dihydronaphthalenes is developed. This difunctionalization proceeds via a sequence of C=C bond sulfonylation, C-C σ-bond cleavage, and intramolecular cyclization, and the experiment result shows that the C-C σ-bond difunctionalization reaction includes a radical process. This strategy provides a simple and convenient route for difunctionalization of C-C bonds with an aromatic carbon and a sulfonyl radical by one-pot construction of a C-S bond and a new C-C bond.

Silver(I)-mediated dual cleavage of C-C and C-O bonds in the reaction of diarylmethylenecyclopropanes with tetrahydrofuran: Synthesis of 4-(3-halobut-3-enyloxy)butyl 2,2,2-trifluoroacetate derivatives

The reaction of methylenecyclopropanes (MCPs) with tetrahydrofuran (THF) proceed smoothly in the presence of AgOC(O)CF3 and electrophilic halogenation reagents to give the corresponding 4-(3-halobut-3-enyloxy)butyl 2,2,2-trifluoroacetate derivatives in moderate yields through dual cleavage of C-C and C-O bonds under mild conditions. Novel 4-(3-halobut-3-enyloxy)butyl 2,2,2-trifluoroacetate derivatives can be synthesized by AgI-mediated reactions of arylmethylenecyclopropanes with tetrahydrofuran at room temperature through dual cleavage of C-C and C-O bonds. Copyright