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1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is a chemical compound characterized by a heterocyclic structure that integrates both a thieno and quinoline ring system. 1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is recognized for its potential as a drug candidate due to its wide array of biological activities, such as anti-inflammatory, anticancer, and anti-microbial properties. It has demonstrated promise in preclinical studies for the treatment of various diseases, including cancer and inflammation. The unique chemical structure and its diverse biological activities render 1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one an intriguing target for ongoing research and potential pharmaceutical development.

28237-99-2

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28237-99-2 Usage

Uses

Used in Pharmaceutical Industry:
1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is used as a potential drug candidate for its anti-inflammatory properties, making it a candidate for the treatment of inflammatory diseases.
1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is used as a potential drug candidate for its anticancer properties, showing promise in preclinical studies for the treatment of various types of cancer.
1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is used as a potential drug candidate for its anti-microbial properties, indicating its potential use in treating microbial infections.
Used in Research and Development:
1,4-dihydrothieno[3,4-b]quinolin-9(3H)-one is used as a subject of research for further exploration of its biological activities and potential therapeutic applications, given its unique chemical structure and demonstrated effectiveness in preclinical studies.

Check Digit Verification of cas no

The CAS Registry Mumber 28237-99-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 28237-99:
(7*2)+(6*8)+(5*2)+(4*3)+(3*7)+(2*9)+(1*9)=132
132 % 10 = 2
So 28237-99-2 is a valid CAS Registry Number.

28237-99-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-dihydro-1H-thieno[3,4-b]quinolin-9-one

1.2 Other means of identification

Product number -
Other names 4H-1,3,4,9-Tetrahydrothieno<3,4-b>chinolin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28237-99-2 SDS

28237-99-2Relevant academic research and scientific papers

Quinoline analogues of ortho-quinodimethane

White,O'Neill,Park,Storr

, p. 5983 - 5986 (1995)

2-Methoxyquinoline 3,4-quinodimethane 4, X = OMe, can be be generated from the quinoline 3,4-fused dihydrothiophene S,S-dioxide 23 and trapped with dienophiles but 4-methoxyquinoline 2,3-quinodimethane 3, X = OMe, cannot be obtained from the corresponding

Dihydrothiophenes as precursors to fused quinolines, quinolones and coumarins via o-quinodimethane intermediates

White, Lindsay A.,Storr, Richard C.

, p. 3117 - 3134 (2007/10/03)

3-Methoxycarbonyl-4-keto-2,5-dihydrothiophene is a convenient starting point for synthesis of a range of 3,4- and 2,3-quinoline and quinolone and coumarin fused dihydrothiophene dioxides. With the exception of the 2,3-quinoline derivatives these all lose sulfur dioxide on thermolysis to give the corresponding o-quinodimethanes which can be intercepted in Diels-Alder reactions.

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