28248-32-0Relevant academic research and scientific papers
Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates
Lackner, Gregory L.,Quasdorf, Kyle W.,Overman, Larry E.
, p. 15342 - 15345 (2013)
A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.
Decarboxylative Alkyl Coupling Promoted by NADH and Blue Light
Chowdhury, Rajdip,Yu, Zhunzhun,Tong, My Linh,Kohlhepp, Stefanie V.,Yin, Xiang,Mendoza, Abraham
, p. 20143 - 20151 (2020/11/13)
Photoexcited dihydronicotinamides like NADH and analogues have been found to generate alkyl radicals upon reductive decarboxylation of redox-active esters without auxiliary photocatalysts. This principle allowed aliphatic photocoupling between redox-activ
A practical and catalytic reductive olefin coupling
Lo, Julian C.,Yabe, Yuki,Baran, Phil S.
supporting information, p. 1304 - 1307 (2014/02/14)
A redox-economic method for the direct coupling of olefins that uses an inexpensive iron catalyst and a silane reducing agent is reported. Thus, unactivated olefins can be joined directly to electron-deficient olefins in both intra- and intermolecular settings to generate hindered bicyclic systems, vicinal quaternary centers, and even cyclopropanes in good yield. The reaction is not sensitive to oxygen or moisture and has been performed on gram-scale. Most importantly, it allows access to many compounds that would be difficult or perhaps impossible to access using other methods.
