282524-06-5Relevant academic research and scientific papers
Stereoselective azepine-ring formation through ene reactions of 3-(alk- 2-enyl)amino-2-cyanoacrolein derivatives
Noguchi, Michihiko,Yamada, Hisashi,Takamura, Shinji,Uchida, Takehiko,Hironaka, Mitsuko,Kakehi, Akikazu,Yamamoto, Hidetoshi
, p. 1489 - 1496 (2007/10/03)
The reaction of 3-[N-(alk-2-enyl)benzylamino]-2-cyanoacroleins 9 with primary amines 12 and 13 gave 4,5-dihydro-1H-azepines 14 and 15 stereoselectively, through an intramolecular ene reaction of the imine derivatives of 9. Similarly, carbonyl-ene reaction
