282524-78-1

Basic information

• Product Name: 3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID
• Synonyms: 3-(9 H-FLUOROEN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID;3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-phenylbutanoic acid;N-FMOC-3-AMINO-4-PHENYLBUTANOIC ACID;3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID
• CAS NO: 282524-78-1
• Molecular Formula: C25H23NO4
• Molecular Weight: 401.45
• Mol File: 282524-78-1.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID(282524-78-1)
• EPA Substance Registry System: 3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID(282524-78-1)

Safety Data

• Hazardous Substances Data: 282524-78-1(Hazardous Substances Data)

Usage

General Description

3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID is a chemical compound with the molecular formula C28H25NO4. It is a derivative of the amino acid phenylbutyric acid, with a fluorine-containing 9-H-fluoren-9-ylmethoxycarbonylamino group attached to the third carbon of the butyric acid side chain. 3-(9 H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-4-PHENYL-BUTYRIC ACID may have potential applications in medicinal and pharmaceutical research, as its structure suggests it may have biological activity and be capable of interacting with biological targets. Its precise properties, uses, and potential reactions with other substances would need to be further studied and understood to fully characterize its behavior and potential applications.

Upstream product

• 172097-41-5 (S)-1-diazo-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-phenylbutan-2-one 
• 35661-40-6 N-Fmoc L-Phe 
• 203854-65-3 ((R)-1-Benzyl-3-diazo-2-oxo-propyl)-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 122-78-1 phenylacetaldehyde 
• 190656-01-0 N-(9-fluorenylmethoxycarbonyloxy)hydroxylamine 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 114645-20-4 (S)-3-amino-4-phenylbutanoic acid trifluoroacetate 
• 103321-57-9 2S-flouren-9-ylmethoxycarbonylamino-3-phenylpropionyl chloride 
• 86123-10-6 Fmoc-D-Phe-OH 

Downstream Products

• 270062-99-2 (S)-3-carboxymethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 1610960-66-1 C₇₂H₁₁₁N₁₃O₉ 

Relevant articles and documents

A Meldrum's Acid Based Multicomponent Synthesis of N-Fmoc-isoxazolidin-5-ones: Entry to N-Fmoc-β-amino Acids

A multicomponent Knoevenagel–aza-Michael cyclocondensation (KaMC) reaction starting from Meldrum's acid has been developed with base-sensitive N-Fmoc-hydroxylamine. The reaction takes place under very mild basic conditions, providing a straightforward synthetic route to various unprecedented N-Fmoc-isoxazolidin-5-ones. Subsequent chemoselective reductive cleavage of the N–O bond in the presence of Zn/AcOH allowed a short synthesis of the corresponding N-Fmoc-β-amino acids.

Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffolds

The most commonly recognized motifs in protein-protein interactions are γ and β turns, which are defined by three to four contiguous amino acids in a peptide sequence. Cyclic tetrapeptides thus represent minimalist turn mimetics, but their usefulness is c

Synthesis of β-amino acids: 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate (TBTU) for activation of Fmoc-/Boc-/Z-α-amino acids

A new and efficient method for the homologation of urethane protected α-amino acids to its β-homomers by the Arndt-Eistert method using TBTU as a coupling agent is described. Several Fmoc-/Boc-/Z-protected α-amino diazoketone derivatives have been obtaine