282534-27-4Relevant academic research and scientific papers
Synthesis of alkaloids from amino acids via N-acyliminium ions generated by one-pot radical decarboxylation-oxidation
Boto, Alicia,Hernández, Rosendo,Suárez, Ernesto
, p. 2899 - 2902 (2000)
A one-pot methodology for the synthesis of α-substituted nitrogen heterocycles from commercial amino acids has been developed. Good stereoselectivity can be achieved with chiral substituted rings. This procedure has been applied to the synthesis of piperidine, pyrrolidine and indolizidinone alkaloids. (C) 2000 Elsevier Science Ltd.
Synthesis of alkaloid analogues from α-amino acids by one-pot radical decarboxylation/alkylation
Boto, Alicia,De Leon, Yolanda,Gallardo, Juan Antonio,Hernandez, Rosendo
, p. 3461 - 3468 (2007/10/03)
A mild, one-pot methodology to obtain α-substituted nitrogen heterocycles from commercial amino acids is reported. This versatile procedure has been applied to the synthesis of different alkaloid analogues in good to excellent yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
