282547-57-3

Basic information

• Product Name: 8-(4-benzyl-piperazin-1-yl)-6-bromo-quinoline
• Synonyms: 8-(4-benzyl-piperazin-1-yl)-6-bromo-quinoline
• CAS NO: 282547-57-3
• Molecular Weight: 382.303
• Mol File: 282547-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(4-benzyl-piperazin-1-yl)-6-bromo-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-benzyl-piperazin-1-yl)-6-bromo-quinoline(282547-57-3)
• EPA Substance Registry System: 8-(4-benzyl-piperazin-1-yl)-6-bromo-quinoline(282547-57-3)

Safety Data

• Hazardous Substances Data: 282547-57-3(Hazardous Substances Data)

Upstream product

• 55-51-6 N,N-bis(2-chloro-ethyl)-benzenemethanamine 
• 10429-82-0 N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride 
• 57339-57-8 8-amino-6-bromoquinoline 

Downstream Products

• 282547-64-2 benzyl-[8-(4-benzyl-piperazin-1-yl)-quinolin-6-yl]-methylamine 

Relevant articles and documents

ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION

Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise (I) wherein: Ra, R1, R2 and R3 are each, independently, hydrogen, or a substituent selected from halogen, CF3, alkyl, alkoxy, MeSO2, amino or aminocarbonyl (each optionally substituted by one or two groups selected from alkyl and benzyl) carboxy, or alkoxycarbonyl; or two adjacent of Ra and R1-4 together can form a 5-7 membered carbocyclic or heterocyclic ring which is optionally substituted by a substituent defined above; R4 is hydrogen, halogen, or alkyl; R5 is hydrogen, alkyl, arylalkyl, or aryl; R6 is hydrogen, halogen, CF3, CN, carbamide, alkoxy or benzyloxy; X1, X2 and X3 are each carbon or one of X1, X2 or X3 may be nitrogen; Y is CH or nitrogen; and Z is carbon or nitrogen; or pharmaceutically acceptable salts thereof.