28267-23-4Relevant articles and documents
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Khorana et al.
, p. 1002 (1957)
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2-Oxoalkyl caged oligonucleotides: One-electron reductive activation into emergence of ordinary hybridization property by hypoxic X-irradiation
Tanabe, Kazuhito,Kanezaki, Hiroshi,Ishii, Hirotake,Nishimoto, Sei-Ichi
, p. 1242 - 1246 (2008/02/03)
Ionizing radiation triggers the activation of caged oligodeoxynucleotides (ODNs) with a 2-oxoalkyl leaving group to give the corresponding normal uncaged strands. We designed and synthesized ODNs caged by a 2-oxopropyl group at a given thymine N(3) positi
TRITYLOXYETHYLAMINO GROUP FOR THE PROTECTION OF PHOSPHORYL GROUP IN OLIGONUCLEOTIDE SYNTHESIS
Tanaka, Toshiki,Yamada, Yasuki,Ikehara, Morio
, p. 5641 - 5644 (2007/10/02)
Trityloxyethylamino group was used for the protection of 5'-phosphoryl group of deoxyribonucleoside.This group is not only protecting group of phosphate also the intermediate for the synthesis of d-ppA and d-pppA.