282717-75-3Relevant academic research and scientific papers
Bite angle effect of bidentate P-N ligands in palladium catalysed allylic alkylationf
Van Haaren, Richard J.,Druijven, Cees J. M.,Van Strijdonck, Gino P. F.,Oevering, Henk,Reek, Joost N. H.,Kamer, Paul C. J.,Van Leeuwen, Piet W. N. M.
, p. 1549 - 1554 (2007/10/03)
Two series of new bidentate P-N ligands have been synthesized. Application of these ligands in the palladium catalysed allylic alkylation of crotyl chloride and cinnamyl chloride leads to the preferential formation of the branched product. A larger bite angle of the ligand leads to higher regioselectivity. Stoichiometric alkylation of the complex [Pd(C4H7){p-MeOC6H4C=N(CH 2)4OPPh2}][O3SCF3] proceeds with 88% regioselectivity to the branched product. The Royal Society of Chemistry 2000.
