282724-29-2

Basic information

• Product Name: (2E,6E)-2,6-bis(3-aminobenzylidene)cyclohexanone
• Synonyms: (2E,6E)-2,6-bis(3-aminobenzylidene)cyclohexanone
• CAS NO: 282724-29-2
• Molecular Weight: 304.392
• Mol File: 282724-29-2.mol

Chemical Properties

• CAS DataBase Reference: (2E,6E)-2,6-bis(3-aminobenzylidene)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,6E)-2,6-bis(3-aminobenzylidene)cyclohexanone(282724-29-2)
• EPA Substance Registry System: (2E,6E)-2,6-bis(3-aminobenzylidene)cyclohexanone(282724-29-2)

Safety Data

• Hazardous Substances Data: 282724-29-2(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 99-61-6 3-nitro-benzaldehyde 
• 42792-81-4 α,α'-bis(3-nitrobenzylidene)cyclohexanone 

Relevant articles and documents

Design, synthesis, anticancer activity and cytotoxicity of novel 4-piperidone/cyclohexanone derivatives

Abstract: Design and synthesis of two series of novel double Schiff-base substituted 4-piperidone/cyclohexanone derivatives, like curcumin analogues, series 1 (1a–d) and 2 (2a–e) were generated and characterized by 1H NMR, 13C NMR, I

Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation

Novel hydroxyl-substituted double Schiff-base 4-piperidone/cyclohexanone derivatives, 3a–e, 4a–e, 5a–d, and 6a–c, were synthesized and fully characterized by 1H NMR, IR and elemental analysis. The cytotoxicity against human carcinoma cell lines

Synthesis, anticancer activity and cytotoxicity of novel double Schiff-base condensed α,β-unsaturated keto derivatives

Five double Schiff-base condensed α,β-unsaturated keto derivatives, as curcumin analogues, were synthesised in three steps. Cyclohexanone, or N-methyl-4-pyridone, and 3-nitrobenzaldehyde (2 equiv.) were subjected to Claisen-Schmidt condensation under acid

Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation

In a continuing study of hybrid compounds containing the α-bromoacryloyl moiety as potential anticancer drugs, we synthesized a novel series of hybrids 4a-h, in which this moiety was linked to a 1,5-diaryl-1,4-pentadien-3-one system. Many of the conjugates prepared (4b, 4c, 4e and 4g) demonstrated pronounced, submicromolar antiproliferative activity against four cancer cell lines. Moreover, compound 4b induced apoptosis through the mitochondrial pathway and activated caspase-3 in a concentration-dependent manner.