283152-38-5

Upstream product

• 15450-73-4 2,5,8(1H)-quinolinetrione 
• 283152-36-3 4-(2-trifluoroacetamidophenyl)-1-(dimethylamino)-1-aza-1,3-butadiene 
• 283152-35-2 o-aminocinnamaldehyde N,N-dimethylhydrazone 
• 283152-37-4 2,2,2-trifluoro-N-[2-(5,8,10-trioxo-1,4,5,8,9,10-hexahydro-pyrido[3,2-g]quinolin-4-yl)-phenyl]-acetamide 

Downstream Products

• 294174-06-4 8-Methoxy-4-(2-trifluoroacetamidophenyl)pyrido[3,2-g]-quinoline-5,10-dione 

Relevant academic research and scientific papers

Pharmaceutical composition based on polyaromatic compounds

A pharmaceutical composition comprising an efficient amount of a compound selected among the compounds of formulae (I) and (II). The compounds have useful cytotoxic properties providing therapeutic application as antitumoral medicine.

Synthesis and characterization of the antitumor activities of analogues of meridine, a marine pyridoacridine alkaloid

Marine compounds with pyridoacridine skeletons are known to exhibit interesting antitumor activities. Among these compounds, meridine has already been reported as having significant antitumor activities in vitro. We synthesized 24 analogues of meridine su

(o-Trifluoroacetamido)cinnamaldehyde Dimethylhydrazone, a Useful Azadiene in the Hetero Diels-Alder Approach to the Pyrido[2,3,4-kl]acridine System

The hetero Diels-Alder reaction between (o-trifluoroacetamido)cinnamaldehyde dimethylhydrazone and several quinones followed by aromatization and hydrolytic cyclization afforded the corresponding pyrido[2,3,4-kl]acridine derivatives in 26-43 percent overall yields.