283177-13-9Relevant academic research and scientific papers
A novel enantiopure tricyclic β-lactam via stereoselective intramolecular nitrilimine cycloaddition
Buttero, Paola Del,Molteni, Giorgio,Pilati, Tullio
experimental part, p. 2607 - 2611 (2010/12/29)
Starting from the Staudinger [2+2] cycloaddition between the 1-azadiene 1 and acetoxyacetylketene, generated in situ from acetoxyacetyl chloride, we developed a seven-step synthesis of the novel azeto[3′,4′:2,3] pyrano[4,5-c]pyrazole skeleton 9 in both ra
An asymmetric synthesis of a 3-hydroxy-β-lactam by keteneimine cycloaddition: Utilization of chiral ketenes from carbohydrates
Borer, Bennett C.,Balogh, Douglas W.
, p. 1039 - 1040 (2007/10/02)
The Staudinger reaction of a chiral carbohydrate-based ketene and an imine proceeds to give, after removal of the sugar, cis-3-hydroxy-β-lactam 7 in moderate yield with good asymmetric induction (70% e.e.).
