283584-90-7

Basic information

• Product Name: 2-Buten-1-ol, 4,4,4-trifluoro-3-phenyl-, (2E)-
• CAS NO: 283584-90-7
• Molecular Formula: C10H9F3O
• Molecular Weight: 202.176
• Mol File: 283584-90-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Buten-1-ol, 4,4,4-trifluoro-3-phenyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Buten-1-ol, 4,4,4-trifluoro-3-phenyl-, (2E)-(283584-90-7)
• EPA Substance Registry System: 2-Buten-1-ol, 4,4,4-trifluoro-3-phenyl-, (2E)-(283584-90-7)

Safety Data

• Hazardous Substances Data: 283584-90-7(Hazardous Substances Data)

Upstream product

• 648425-37-0 (2Z)-3-trifluoromethyl-3-phenylprop-2-en-1-ol 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 56210-74-3 ethyl (2E)-3-trifluoromethyl-3-phenylprop-2-enoate 
• 10075-06-6 ethyl 3-phenyl-4,4,4-trifluoro-2-butenoate (E,Z) 
• 154841-07-3 Acetic acid (E)-4,4,4-trifluoro-3-phenyl-but-2-enyl ester 

Relevant articles and documents

Spatiotemporal Control of Pre-existing Alkene Geometry: A Bio-Inspired Route to 4-Trifluoromethyl-2H-chromenes

Routes to prepare C4-trifluoromethyl analogues of the 2H-chromene scaffold are scarce: this is particularly striking given the importance of fluorine in pharmaceutical development. To address this limitation, a facile strategy has been developed that is reliant on catalytic, geometric isomerization of easily accessible allylic alcohols (up to >95:5) followed by intramolecular cyclization via Pd catalysis (up to 96%). This concise biomimetic approach emulates the photoisomerization/cyclization cascade inherent to phenylpropanoid biosynthesis.

Synthesis of β-CF3 ketones from trifluoromethylated allylic alcohols by ruthenium catalyzed isomerization

This work describes the optimization process for the synthesis of β-trifluoromethylated ketones from trifluoromethylated allylic alcohols. This transformation proceeds through a ruthenium catalyzed isomerization under mild conditions with high atom econom

Synthese d'Amines Primaires Allyliques γ-trifluoromethylees

Des amines primaires allyliques substituees par un groupement trifluoromethyle ont ete preparees par une voie de synthese faisant intervenir intermediairement des azotures allyliques.Deux autres approches d'obtention de ces amines ont ete essayees: reacti