283611-27-8

Basic information

• Product Name: N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester
• Synonyms: N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester
• CAS NO: 283611-27-8
• Molecular Weight: 350.352
• Mol File: 283611-27-8.mol

Chemical Properties

• CAS DataBase Reference: N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester(283611-27-8)
• EPA Substance Registry System: N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester(283611-27-8)

Safety Data

• Hazardous Substances Data: 283611-27-8(Hazardous Substances Data)

Upstream product

• 40195-27-5 (1-methoxy-2-phenylvinyloxy)trimethylsilane 
• 149552-41-0 2-nitro-N-(phenyl-λ³-iodaneylidene)benzenesulfonamide 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 

Downstream Products

• 283611-42-7 N-methyl-N-(o-nitrobenzenesulfonyl)-L-phenylglycine methyl ester 
• 856865-85-5 N-α-methyl-N-α-(o-nitrobenzenesulfonyl)-L-phenylglycine 

Relevant articles and documents

N-monoalkylation of α-amino acid esters under solid-liquid PTC conditions

N-(2-Nitrophenylsulfonyl)- (o-NBS-AA-OMe, 4) and N-(4- Nitrophenylsulfonyl)-α-amino acid methyl esters (p-NBSAA-OMe, 5) were N- alkylated with a variety of alkyl halides 6 under solid-liquid phase-transfer catalysis (SL-PTC) conditions, affording the alkylated products o-NBS-N-R2- AA-OMe 7 and p-NBS-N-R2-AA-OMe 8 in excellent yields without any detectable racemization.

Enantioselective amination of silylketene acetals with (N-arylsulfonylimino)phenyliodinanes catalyzed by chiral dirhodium(II) carboxylates: asymmetric synthesis of phenylglycine derivatives

The first catalytic enantioselective amination of silylketene acetals with (N-arylsulfonylimino)phenyliodinanes is described. The reaction of silylketene acetals derived from methyl phenylacetates with [N-(2-nitrophenylsulfonyl)imino]phenyliodinane (NsN =

Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis

Nα-Methylamino acid containing peptides exhibit interesting therapeutic profiles and are increasingly recognized as potentially useful therapeutics. Unfortunately, their synthesis is hampered by the high price and unavaibility of many Nα/