28383-15-5 Usage
Uses
Used in Forensic Applications:
1-(1,2-diphenylethyl)piperidine hydrochloride is used as a forensic tool for the identification and analysis of designer drugs, specifically those related to the NMDA receptor channel blocker, MK 801. Its role in this application is to aid in the detection and differentiation of such substances in criminal investigations.
Used in Research Applications:
1-(1,2-diphenylethyl)piperidine hydrochloride is used as a research compound for studying the interactions and effects of NMDA receptor channel blockers on the brain. Its application in this context is to provide insights into the mechanisms of action and potential therapeutic uses of these types of compounds.
Used in Neuroprotective Applications:
1-(1,2-diphenylethyl)piperidine hydrochloride is used as a neuroprotective agent for the treatment of brain injury following hypoxia. Its application in this area is based on its ability to inhibit MK 801 binding to NMDA receptors, which may help in mitigating the effects of brain injury and promoting recovery.
Check Digit Verification of cas no
The CAS Registry Mumber 28383-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,3,8 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 28383-15:
(7*2)+(6*8)+(5*3)+(4*8)+(3*3)+(2*1)+(1*5)=125
125 % 10 = 5
So 28383-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H23N.ClH/c1-4-10-17(11-5-1)16-19(18-12-6-2-7-13-18)20-14-8-3-9-15-20;/h1-2,4-7,10-13,19H,3,8-9,14-16H2;1H
28383-15-5Relevant academic research and scientific papers
NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds
Berger, Michael L.,Schweifer, Anna,Rebernik, Patrick,Hammerschmidt, Friedrich
experimental part, p. 3456 - 3462 (2009/09/30)
We resolved 1,2-diphenylethylamine (DPEA) into its (S)- and (R)-enantiomer and used them as precursors for synthesis of (S)- and (R)-1-(1,2-diphenylethyl)piperidine, flexible homeomorphs of the NMDA channel blocker MK-801. We also describe the synthesis o
