28401-39-0Relevant articles and documents
ENZYMATIC KINETIC RESOLUTION OF CYANOHYDRIN ACETATES AND ITS APPLICATION TO THE SYNTHESIS OF (S)-(-)-FRONTALIN
Ohta, Hiromichi,Kimura, Yoichi,Sugano, Yasushi,Sugai, Takeshi
, p. 5469 - 5476 (2007/10/02)
Kinetic resolution of racemic 1-cyano-1-methylalkyl and alkenyl acetates has been achieved on incubation with Pichia miso IAM 4682, which hydrolyzed selectively the (R)-enantiomer, leving behind the (S)-enantiomer intact.The chiral 1-cyano-1-methyl-5-hexenyl acetate thus obtained was converted to (S)-frontalin via unsaturated diol.
CONVENIENT SYNTHETIC ROUTE TO (+/-) -FRONTALIN
Kongkathip, Boonsong,Sokkho, Rongsan,Kongkathip, Ngampong
, p. 1849 - 1850 (2007/10/02)
(+/-)-Frontalin was synthesized in a few steps sequence starting from ethyl acetoacetate involving intramolecular cyclization using palladium chloride as catalyst