284026-45-5

Upstream product

• 284026-43-3 (3R,7aR)-7a-Butyl-6-methyl-3-phenyl-1,7a-dihydro-pyrrolo[1,2-c]oxazol-5-one 
• 284026-41-1 (3R,7aR)-6-Methyl-7a-(2-nitro-butyl)-3-phenyl-1,7a-dihydro-pyrrolo[1,2-c]oxazol-5-one 

Downstream Products

• 284026-49-9 (2R,4S)-4-Butyl-3-(2-oxo-propionyl)-2-phenyl-oxazolidine-4-carboxylic acid 
• 284026-47-7 (2R,4S)-4-Butyl-3-(2-oxo-propionyl)-2-phenyl-oxazolidine-4-carbaldehyde 

Relevant academic research and scientific papers

A new approach for construction of quarternary chiral centers: Preparation of α-branched serine derivatives

In the presence of a Lewis acid, the Michael-type reaction of (3R)-5- tert-butyldimethylsiloxy-3-phenyl-1H-pyrrolo[1,2-c]oxazole (1) with nitro olefins smoothly occurred to give 7a-alkylated pyrrolo[1,2-c]oxazol-5-ones (2) in good yields. The products (2)