284026-45-5Relevant articles and documents
A new approach for construction of quarternary chiral centers: Preparation of α-branched serine derivatives
Uno, Hidemitsu,Kasahara, Ken-Ichi,Ono, Noboru
, p. 1011 - 1016 (2007/10/03)
In the presence of a Lewis acid, the Michael-type reaction of (3R)-5- tert-butyldimethylsiloxy-3-phenyl-1H-pyrrolo[1,2-c]oxazole (1) with nitro olefins smoothly occurred to give 7a-alkylated pyrrolo[1,2-c]oxazol-5-ones (2) in good yields. The products (2)