284027-36-7 Usage
Uses
Used in Organic Synthesis:
8-TrifluoroMethyl-1,2,3,4-tetrahydro-isoquinoline is utilized as a building block in organic synthesis for the preparation of various biologically active molecules. Its trifluoromethyl group and isoquinoline core contribute to the structural diversity and potential reactivity of the synthesized compounds.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, 8-TrifluoroMethyl-1,2,3,4-tetrahydro-isoquinoline serves as a key component in the development of new drugs. Its incorporation into drug candidates can enhance their pharmacological properties, such as potency, selectivity, and bioavailability.
Used in Pharmaceutical Applications:
8-TrifluoroMethyl-1,2,3,4-tetrahydro-isoquinoline is being studied for its potential pharmaceutical applications, particularly in the treatment of neurological and psychiatric disorders. Its unique structure may offer novel mechanisms of action and therapeutic benefits in these areas.
Used in Drug Design and Structure-Activity Relationship Studies:
8-TrifluoroMethyl-1,2,3,4-tetrahydro-isoquinoline's distinctive properties make it a valuable tool in exploring structure-activity relationships and drug design. Researchers can use 8-TrifluoroMethyl-1,2,3,4-tetrahydro-isoquinoline to investigate how structural modifications impact the biological activity of drug candidates, thereby guiding the optimization of lead compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 284027-36-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,0,2 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 284027-36:
(8*2)+(7*8)+(6*4)+(5*0)+(4*2)+(3*7)+(2*3)+(1*6)=137
137 % 10 = 7
So 284027-36-7 is a valid CAS Registry Number.
284027-36-7Relevant academic research and scientific papers
SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF
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, (2018/08/03)
Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.
Substituted phenyl methanones
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Page/Page column 16, (2008/06/13)
The present invention relates to compounds of general formula IA or IB wherein X1 and X2 are each independently N or C—R″ and R1, R2,R3, R4, R5, and R6 are as defined
TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
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Page/Page column 103, (2010/02/07)
The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
