284044-37-7Relevant academic research and scientific papers
Acylsulfamide inhibitors of factor VIIa
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Page 26-27, (2010/02/09)
Compounds having the general formula I are useful for inhibiting serine protease enzymes, such as Tissue Factor VIIa, factor Xa, thrombin and kallikrein and have improved permeability properties. These compounds may be used in methods of preventing and/or
Serine protease inhibitors
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, (2008/06/13)
Compounds having the structure shown below wherein A, B, N1, N2, X, Y, Q, R2, R5and R6are as defined herein are useful to inhibit serine protease enzymes, such as TF/factor VIIa factor Xa, thrombin and kallikrein. These compounds may be used in methods of preventing and/or treating clotting disorders.
