28416-91-3

Basic information

• Product Name: (S)-benzyl (1-azido-1-oxopropan-2-yl)carbamate
• Synonyms: (S)-benzyl (1-azido-1-oxopropan-2-yl)carbamate
• CAS NO: 28416-91-3
• Molecular Weight: 248.241
• Mol File: 28416-91-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (S)-benzyl (1-azido-1-oxopropan-2-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-benzyl (1-azido-1-oxopropan-2-yl)carbamate(28416-91-3)
• EPA Substance Registry System: (S)-benzyl (1-azido-1-oxopropan-2-yl)carbamate(28416-91-3)

Safety Data

• Hazardous Substances Data: 28416-91-3(Hazardous Substances Data)

Upstream product

• 17350-66-2 N-benzyloxycarbonylalaninehydrazid 
• 1142-20-7 N-Cbz-Ala 

Downstream Products

• 93788-20-6 (S,S)-bis(N-benzyloxycarbonylalanyl)diaza-18-crown-6 
• 94068-22-1 N,N'-bis(benzyloxycarbonyl)ethane-1,1-diamine 
• 64789-41-9 N-benzyloxycarbonyl-N'-t-butyloxycarbonylethane-1,1-diamine 
• 76863-49-5 1-benzyloxycarbonylaminoethyl isocyanate 
• 102195-74-4 N,N'-bis(1-benzyloxycarbonylaminoethyl)urea 
• 133463-33-9 Boc-Ser-Pro-Val-Thr-Leu-Asp(OBzl)-Leu-Arg(NO₂)-Tyr-OMe 
• 88491-33-2 (S)-N-benzyloxycarbonyl-N'-ethoxycarbonylethane-1,1-diamine 

Relevant articles and documents

3,3-dichloro-1,2-diphenylcyclopropene (CPICL)-mediated synthesis of n α-protected amino acid azides and α-ureidopeptides

Rapid synthesis of acid azides via in situ generation of acid chlorides using CPICl as chlorinating agent from the corresponding Nα- protected amino acids is described. Also the conversion of acid azides into ureidopeptides through the Curtius rearrangement under ultrasonication is delineated. The mildness of the protocol renders the acid-sensitive substrates to afford the corresponding amino acid azides and ureidopeptides in good yields. Diphenylcyclopropenone has also been recovered from the reaction mixture and reused. Georg Thieme Verlag Stuttgart New York.

Facile one step synthesis of acyl azides and Nα-Fmoc/Boc/Z protected amino acid azides employing benzotriazole-1-yl-oxy-tris- (dimethylamino)-phosphonium hexafluorophosphate (BOP)

A simple route for the preparation of acyl azides from the corresponding carboxylic acids employing the peptide-coupling agent BOP is described. The procedure is simple, clean and high yielding. The chemistry is also extended to the preparation of several urethane protected amino acid azides (eight examples) as well.

Amino acids and peptides. XXIX. Synthesis of peptide fragments related to active center of eglin c and studies on the relationship between their structure and their inhibitory activity against cathepsin G and α-chymotrypsin

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