2844-09-9

Upstream product

• 870-63-3 prenyl bromide 
• 611-70-1 phenyl isopropyl ketone 
• 24083-46-3 2,5-dimethyl-1-phenyl-4-hexen-1-one 
• 74-88-4 methyl iodide 
• 556-82-1 3-methyl-2-buten-1-ol 
• 13899-89-3 2,2,5-trimethylhex-4-enenitrile 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1616603-15-6 4,4-dimethyl-5-phenyl-2-(prop-1-en-2-yl)-3,4-dihydro-2H-pyrrole 
• 1616603-32-7 2,2,5-trimethyl-1-phenylhex-4-en-1-one acetyloxime 
• 830345-43-2 C₂₂H₃₈O₄Si 
• 830345-39-6 3,3,6-trimethyl-2-phenyl-1,5-heptadiene 

Relevant academic research and scientific papers

Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines

A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.

Silver-promoted cascade radical cyclization of γ,δ-unsaturated oxime esters with P(O)H compounds: synthesis of phosphorylated pyrrolines

A cascade radical cyclization was realized for the first silver-promoted imino-phosphorylation of γ,δ-unsaturated oxime esters, which provided a step-economical and redox-neutral route to access a variety of phosphorylated pyrrolines in good to excellent yields. Moreover, a new bulky trivalent phosphine ligand with a pyrroline motif was obtained through a deoxidation process.

Copper-catalyzed cyclization and azidation of γ,δ-unsaturated ketone O-benzoyl oximes

An intramolecular imination/azidation sequence has been realized through the tetrakis(acetonitrile)copper(I) hexafluorophophate [Cu(CH3CN)4PF6]-catalyzed reaction of γ,δ-unsaturated ketone O-benzoyl oximes with trimethylsi

Copper-catalyzed 5-endo-trig cyclization of ketoxime carboxylates: A facile synthesis of 2-arylpyrroles

A novel and facile copper-catalyzed 5-endo-trig cyclization of ketoxime carboxylates for the synthesis of 2-arylpyrroles has been developed. The reaction tolerates a range of functional groups and is a practical procedure for rapid synthesis of 2-arylpyrroles in high yields under mild conditions. the Partner Organisations 2014.

Synthesis of cyclic peroxides by chemo- and regioselective peroxidation of dienes with Co(II)/O2/Et3SiH

(Chemical Equation Presented). In the competitive peroxidation of mixtures of two alkenes with Co(II)/O2/Et3SiH, it was found that the relative reactivities of the alkene substrates are influenced by three major factors:. (1) relative stability of the intermediate carbon-centered radical formed by the reaction of the alkene with HCo(III) complex, (2) steric effects around the C=C double bond, and (3) electronic factors associated with the C=C double bond. Consistent with results from simple alkenes, the chemo-and regioselective peroxidation of dienes was also realized. Depending on the diene structure, the product included not only the expected acyclic unsaturated triethylsilyl peroxides but also 1,2-dioxolane and 1,2-dioxane derivatives via intramolecular cyclization of the unsaturated peroxy radical intermediates.