28442-78-6 Usage
Uses
Used in Chemical Synthesis:
2-Chloroisophthalonitrile is used as a chemical intermediate for the synthesis of organic compounds, leveraging its reactivity to facilitate the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Chloroisophthalonitrile is utilized as a key ingredient in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Dye and Pigment Production:
2-Chloroisophthalonitrile is employed as an intermediate in the production of dyes and pigments, where its chemical properties are harnessed to create a diverse palette of colorants for various applications.
It is crucial to handle 2-Chloroisophthalonitrile with care due to its potential hazards to human health and the environment, necessitating proper control and management in industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 28442-78-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,4 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 28442-78:
(7*2)+(6*8)+(5*4)+(4*4)+(3*2)+(2*7)+(1*8)=126
126 % 10 = 6
So 28442-78-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H3ClN2/c9-8-6(4-10)2-1-3-7(8)5-11/h1-3H
28442-78-6Relevant academic research and scientific papers
Three groups good, four groups bad? Atropisomerism in ortho-substituted diaryl ethers
Betson, Mark S.,Clayden, Jonathan,Worrall, Christopher P.,Peace, Simon
, p. 5803 - 5807 (2007/10/03)
(Chemical Equation Presented) Bring on the substitute: Even outside of macrocyclic structures, such as vancomycin, appropriate substitution can give rise to atropisomerism in diaryl ethers. Stereochemical stability about the Ar-OAr axis at room temperature or above is possible when neither of the rings is symmetrically substituted and when at least one ring carries an ortho tert-butyl group or equivalent.
Directed Ortho Lithiation of Isophthalonitrile. New Methodology for the Synthesis of 1,2,3-Trisubstituted Benzenes
Krizan, Timothy D.,Martin, J. C.
, p. 2681 - 2682 (2007/10/02)
The lithiation of 1,3-dicyanobenzene with lithium diisopropylamide occurs in high yield, regiospecifically at the 2-position, to give aryllithium species stable at temperatures below -90 deg C.
