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FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID, also known as FMOC-DL-Amino Acid Chloride, is a chemical compound that serves as a key component in the synthesis of pharmaceuticals and peptide-based drugs. It is a derivative of the amino acid alanine, featuring a fluorogenic FMOC (9-fluorenylmethoxycarbonyl) protecting group. This group is instrumental in solid-phase peptide synthesis, allowing for the efficient and controlled assembly of peptide sequences. FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID is characterized by its white to off-white solid form and a melting point of 46-48°C. It exhibits solubility in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), facilitating its use in various chemical processes.

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  • 284492-14-4 Structure
  • Basic information

    1. Product Name: FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID
    2. Synonyms: FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID;RARECHEM AK HF T319;N-FMOC-3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID;Fmoc-(RS)-3-Amino-3-(2-chlorophenyl)-propionic acid
    3. CAS NO:284492-14-4
    4. Molecular Formula: C24H20ClNO4
    5. Molecular Weight: 421.87
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 284492-14-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 635.6°Cat760mmHg
    3. Flash Point: 338.2°C
    4. Appearance: /
    5. Density: 1.336g/cm3
    6. Vapor Pressure: 4.98E-17mmHg at 25°C
    7. Refractive Index: 1.637
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.22±0.10(Predicted)
    11. CAS DataBase Reference: FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID(284492-14-4)
    13. EPA Substance Registry System: FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID(284492-14-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 284492-14-4(Hazardous Substances Data)

284492-14-4 Usage

Uses

Used in Pharmaceutical Synthesis:
FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID is used as a reagent in the chemical synthesis of peptides for research and pharmaceutical applications. Its fluorogenic FMOC protecting group is particularly advantageous for solid-phase peptide synthesis, enabling the controlled and efficient assembly of peptide sequences, which is crucial for the development of new drugs and therapeutic agents.
Used in Research Applications:
In the field of research, FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID is utilized as a building block for the synthesis of various peptide sequences. Its unique properties, such as the presence of the FMOC protecting group and solubility in organic solvents, make it a valuable tool for studying the structure, function, and interactions of peptides in biological systems.
Used in Peptide Drug Development:
FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID is employed as a key component in the development of peptide-based drugs. Its role in solid-phase peptide synthesis allows for the creation of novel therapeutic agents with specific biological activities, potentially leading to the discovery of new treatments for various diseases and conditions.
Used in Chemical Synthesis Industry:
In the chemical synthesis industry, FMOC-DL-3-(2-CHLOROPHENYL)-3-AMINO-PROPIONIC ACID is used as a versatile reagent for the synthesis of a wide range of peptide-based compounds. Its properties, such as solubility in organic solvents and the presence of the FMOC protecting group, make it suitable for various chemical processes, including the production of pharmaceuticals, agrochemicals, and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 284492-14-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,4,9 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 284492-14:
(8*2)+(7*8)+(6*4)+(5*4)+(4*9)+(3*2)+(2*1)+(1*4)=164
164 % 10 = 4
So 284492-14-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H20ClNO4/c25-21-12-6-5-11-19(21)22(13-23(27)28)26-24(29)30-14-20-17-9-3-1-7-15(17)16-8-2-4-10-18(16)20/h1-12,20,22H,13-14H2,(H,26,29)(H,27,28)

284492-14-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-chlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:284492-14-4 SDS

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