Cas 284496-19-1,ethyl 3-{[3-(trifluoromethyl)phenyl]methyl}-1H-indole-2-carboxylate

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Check Digit Verification of cas no

The CAS Registry Mumber 284496-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,4,9 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 284496-19:
(8*2)+(7*8)+(6*4)+(5*4)+(4*9)+(3*6)+(2*1)+(1*9)=181
181 % 10 = 1
So 284496-19-1 is a valid CAS Registry Number.

284496-19-1Upstream product

623-48-3 ethyl iodoacetae

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284496-19-1Relevant academic research and scientific papers

1H-INDOLE-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS PPAR MODULATORS

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Page/Page column 78-79, (2008/06/13)

The present invention relates to certain indole derivatives that are modulators of PPAR, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine.

Synthesis of 2-acyl- and 2-ethoxycarbonyl-3-alkylindoles from o-alkynyltrifluoroacetanilides

Arcadi, Antonio,Cacchi, Sandro,Fabrizi, Giancarlo,Marinelli, Fabio

, p. 647 - 649 (2007/10/03)

The reaction of readily available o-alkynyltrifluoroacetanilides with ethyl iodoacetate, ethyl bromoacetate or α-bromoke-tones in the presence of K2CO3 affords 2-ethoxycarbonyl- and 2-acyl-3-alkylindoles in good to high yield. The synthesis proceeds via an in situ sequential alkylation-cyclization process. Thieme Stuttgart.

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