28458-19-7 Usage
Uses
Used in Pharmaceutical Industry:
Z-PHE-HIS-LEU-OH is used as a potential therapeutic agent for pain management due to its ability to modulate the body's response to pain and stress. It is being studied for its potential interactions with opioid receptors and its role in neuronal signaling pathways, which could lead to the development of new drugs for treating pain.
Used in Neurobiological Research:
Z-PHE-HIS-LEU-OH is used as a research tool in the field of neurobiology to investigate the mechanisms of pain perception and stress response. Its interactions with opioid receptors and involvement in neuronal signaling pathways provide valuable insights into the development of novel therapeutic strategies for managing pain and stress-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 28458-19-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,5 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 28458-19:
(7*2)+(6*8)+(5*4)+(4*5)+(3*8)+(2*1)+(1*9)=137
137 % 10 = 7
So 28458-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C29H35N5O6/c1-19(2)13-25(28(37)38)33-27(36)24(15-22-16-30-18-31-22)32-26(35)23(14-20-9-5-3-6-10-20)34-29(39)40-17-21-11-7-4-8-12-21/h3-12,16,18-19,23-25H,13-15,17H2,1-2H3,(H,30,31)(H,32,35)(H,33,36)(H,34,39)(H,37,38)
28458-19-7Relevant academic research and scientific papers
Mechanism of enantioselective ester cleavage by histidine-containing peptides at a micellar interface. 2. Effect of changing peptide chain length
Cleij, Marco C.,Drenth, Wiendelt,Nolte, Roeland J. M.
, p. 459 - 468 (2007/10/02)
Chiral p-nitrophenyl esters derived from the amino acid phenylalanine are cleaved by various histidine-containing tripeptides and higher oligopeptides as catalysts at a micellar interface.It is assumed that the oligopeptides adopt an internally hydrogen-b
