28458-49-3

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 88-05-1 2,4,6-trimethylaniline 

Downstream Products

• 105201-09-0 2-amino-2',4',6'-trimethyldiphenylamine hydrochloride 
• 28448-17-1 N-(2’,4’,6’-trimethylphenyl)-1,2-phenylenediamine 
• 1351520-09-6 C₂₂H₁₉N₃O 
• 1351520-10-9 C₂₂H₁₉N₃O₂ 
• 134030-22-1 N,N'-bis(2,6-diisopropylphenyl)ethane-1,2-diamine 
• 82757-39-9 1-(2,4,6-trimethylphenyl)benzotriazole 
• 613-15-0 2-methylacridine 

Relevant academic research and scientific papers

Addition of E-H (E = N, P, C, O, S) Bonds to Heterocumulenes Catalyzed by Benzimidazolin-2-iminato Actinide Complexes

The synthesis and characterization of benzimidazolin-2-iminato actinide(IV) complexes [(BimR1/R2N)An(N{SiMe3}2)3] (An = U, Th) (1-6) is reported. All complexes were obtained in high yields, and their solid state structures were established through single-crystal X-ray diffraction analysis. Using 1-6 as precatalysts, the addition of mono- and bifunctional E-H (E = N, P, C, O, S) substrates to various heterocumulenes, including carbodiimides, isocyanates, and isothiocyanates, was investigated, affording the respective addition products in high yields under very mild reaction conditions. Various amines were applicable to this reaction, indicating a large scope capability of amine nucleophiles for the insertion process.

ELECTROACTIVE METAL COMPLEXES

Disclosed is a compound having Formula I: In Formula I: Ar is aryl or deuterated aryl; R1 and R2 are the same or different and can be alkyl, silyl, aryl, deuterated alkyl, deuterated silyl, or deuterated aryl; R3-R5/

Square planar nickel(II) complexes with halogenated o- diiminobenzosemiquinonato ligation: Synthesis, characterization, and redox property

Seven square planar bis(o-diiminobenzosemiquinonato)nickel(II) complexes, [Ni(o-C6H4(NH)(NAr))2] (Ar=Mes, 1; p-F-C 6H4, 2; p-Cl-C6H4, 3), [Ni(o-4,5-F2-C6H2(NH)(NPh))2] (4), and [Ni(o-4,5-Cl2-C6H2(NH)(NAr))2] (Ar=Ph, 5; 2,6-F2-C6H3, 6; 2,6-Cl 2-C6H3, 7), have been synthesized and characterized by 1H NMR, 13C NMR, 19F NMR, IR, UV-Vis-NIR, elemental analyses, HRMS, as well as single-crystal X-ray diffraction studies (1 and 7). The cyclic voltammograms of these complexes exhibit two reversible redox processes of [NiL2]0/1- and [NiL2]1-/2-, and one irreversible process of [NiL 2]0/2+. Substituent effects on the redox properties of these complexes, in addition with those of the known complexes [Ni(o-C 6H4(NH)(NPh))2] (8) and [Ni(o-3,5-Bu t2-C6H2(NH)2) 2] (9), are identified by comparing the half-wave potentials of the reduction waves, as 1≈92] parallels the electron-donating and -withdrawing ability of the substituent group. Reduction of 1 with one or two equivalents of sodium metal in THF has led to the isolation of [Na(THF) 3][1] and [Na(THF)3]2[1]. The structure data of these two complexes revealed by low-temperature X-ray crystallography suggest their corresponding electronic structures of [NiII(1L ·1-)(1L2-)]1- and [Ni II(1L2-)2]2-, which are in line with those of [9]n (n=1-, 2-) suggested by spectroelectrochemical study. Copyright

Selective iron-catalyzed oxidation of benzylic and allylic alcohols

A convenient and selective oxidation of alcohols with hydrogen peroxide to give aldehydes and ketones has been developed. Using in situ generated iron chloride complexes [Fe(L3)2Cln] [n=0-1, L3 =6-(N-phenylbenzimidazoyl)-2-pyridinecarboxylic acid], aldehydes and ketones were obtained in good yield and excellent selectivity after a short reaction time at room temperature. Copyright

Synthesis and structure-activity relationship of imidazo[1,2-a] benzimidazoles as corticotropin-releasing factor 1 receptor antagonists

8-Aryl-1,3a,8-triaza-cyclopenta[a]indenes represent a novel series of high binding affinity corticotropin-releasing factor 1 receptor antagonists. Here, we report their synthesis, SAR, and pharmacokinetic properties of compound 8e (Ki = 23 nM).

Generation and Rearrangement of 4aH-carbazoles

The benzotriazoles (12a-c) bearing ortho-blocked 1-aryl substituents have been decomposed thermally by flash vacuum pyrolysis, and photochemically by irradiation in acetonitrile at 254 nm.The pyrolyses are complex giving mainly mono- and di-methylcarbazoles from (12a), di- and trimethylcarbazoles from (12b), and a tetra- and a penta-methylcarbazole from (12c).All of these products could be formed by generation of 4aH-carbazole intermediates (24) with subsequent thermally-allowed sigmatropic rearrangements (Scheme 6).The photolyses give a different set of products consisting mainly of the cyclopentaquinolines (27a-c) from (12a-c), respectively.These products could be formed from the same 4aH-carbazoles (24) which now undergo photochemical, aza-di-?-methane, rearrangements to give intermediates (29) and hence products (27) (Scheme 7).The 4a-methyl intermediate (29c) is intercepted as the adduct (30) in an extended cycloaddition reaction with acrylonitrile.Key reaction products were synthesized by independent methods.