284663-03-2Relevant academic research and scientific papers
A second generation synthesis of the MBr1 (Globo-H) breast tumor antigen: New application of the n-pentenyl glycoside method for achieving complex carbohydrate protein linkages
Allen,Allen,Zhang,Williams,Zatorski,Ragupathi,Livingston,Danischefsky
, p. 1366 - 1375 (2007/10/03)
A new synthesis of the hexasaccharide MBr1 antigen (globo-H) is reported. A revised construction with improved efficiency was necessary because an anti-cancer vaccine containing this antigen is entering phase II and phase III clinical trials for prostate
