284663-05-4

Upstream product

• 165816-38-6 (2R,3S,4S,5R,6S)-3,5-Bis-benzyloxy-2-benzyloxymethyl-6-fluoro-4-(4-methoxy-benzyloxy)-tetrahydro-pyran 
• 284663-04-3 Pent-4-enyl 2,2',3,3',6,6'-hexa-O-benzyl-β-D-lactoside 
• 949489-27-4 p-tolyl 2,4,6-tri-O-benzyl-3-O-(p-methoxybenzyl)-1-thio-β-D-galactopyranoside 

Relevant academic research and scientific papers

A practical total synthesis of globo-H for use in anticancer vaccines

(Chemical Equation Presented) An improved synthesis of the hexasaccharide MBr1 antigen (globo-H) is reported. Enhanced efficiency in the synthesis was necessary for the scale-up production of globo-H, in order to advance globo-H-based anticancer vaccines

A second generation synthesis of the MBr1 (Globo-H) breast tumor antigen: New application of the n-pentenyl glycoside method for achieving complex carbohydrate protein linkages

A new synthesis of the hexasaccharide MBr1 antigen (globo-H) is reported. A revised construction with improved efficiency was necessary because an anti-cancer vaccine containing this antigen is entering phase II and phase III clinical trials for prostate