284668-07-1Relevant academic research and scientific papers
Syntheses of isocitric acid derivatives and biological evaluation
Tori, Motoo,Sono, Yoko,Nakashiba, Yasuyo,Hamada, Noriko,Sono, Masakazu,Asakawa, Yoshinori,Suganuma, Masami,Okabe, Sachiko,Fujiki, Hirota
, p. 3095 - 3098 (2007/10/03)
Isocitric acid methyl esters and their derivatives have been synthesized and their biological activities, superoxide release inhibition and tumor necrosis factor-alpha (TNFα)'s release inhibition, have been studied. Linoleic and linolenic acid derivatives showed strong activity against TNFα's release inhibition comparable to sarcophytol A and cryptoporic acid E. (C) 2000 Elsevier Science Ltd.
