2848-06-8

Usage

Uses

Used in Pharmaceutical Industry:
(CARBOXYMETHYL-CYCLOHEXYL-AMINO)-ACETIC ACID is used as a compound with potential pharmaceutical applications due to its unique structure containing a carboxyl group, a cyclohexyl group, and an amino group. Its chelating and complexing abilities may be harnessed for drug formulation and development.
Used in Chemical Industry:
In the chemical industry, (CARBOXYMETHYL-CYCLOHEXYL-AMINO)-ACETIC ACID is used as a compound with potential applications in various chemical processes. The presence of reactive functional groups, such as the carboxyl and amino groups, suggests its utility in metal ion binding and other complexing reactions, which could be valuable in the synthesis of new compounds or materials.

Upstream product

• 108-91-8 cyclohexylamine 
• 79-11-8 chloroacetic acid 

Relevant academic research and scientific papers

Enantioselective Synthesis of cis- A nd trans-Borocyclopropylmethanol: Simple Building Blocks to Access Heterocycle-Substituted Cyclopropylmethanols

An enantioselective and non-oxidative methodology was developed to obtain enantioenriched cyclopropyl boronates using a diethanolamine-promoted selective decomplexation of dioxaborolane. The non-oxidative decomplexation of the dioxaborolane ligand from the cyclopropylmethoxide species formed in the dioxaborolane-mediated Simmons-Smith cyclopropanation reaction provided the enantio?-enriched CIDA-based (CIDA = N-cyclohexyliminodiacetic acid) boro?-cyclopropane in 92% yield and 95.6:4.4 er. A robustness screen has shown diethanolamine to be compatible with esters, carbamates and N-heterocycles, providing a tool to access enantioenriched cyclopropanes carrying not only base-sensitive but oxidizable functional groups as well. Diethanolamine was found to be compatible with the modified zinco-cyclopropanation reaction of allyl alcohol to remove residual dioxaborolane from the corresponding cis-N-heterocycle cyclopropylmethanol, thereby leading to improved yields.