28484-87-9 Usage
General Description
6-(pentylamino)pyrimidine-2,4(1H,3H)-dione, also known as pentoxifylline, is a chemical compound with a variety of medicinal properties. It is commonly used as a vasodilator to improve blood flow and increase circulation, making it effective in treating conditions such as intermittent claudication, a condition characterized by leg pain and cramping due to reduced blood flow. Pentoxifylline has also been shown to have anti-inflammatory and antioxidant properties, making it useful in the treatment of conditions such as peripheral artery disease, diabetic neuropathy, and chronic venous insufficiency. Additionally, it has been investigated for its potential to reduce symptoms of sickle cell disease and improve outcomes in patients with acute pancreatitis. Overall, 6-(pentylamino)pyrimidine-2,4(1H,3H)-dione has a range of therapeutic applications and continues to be studied for its potential in treating various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 28484-87-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,8 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28484-87:
(7*2)+(6*8)+(5*4)+(4*8)+(3*4)+(2*8)+(1*7)=149
149 % 10 = 9
So 28484-87-9 is a valid CAS Registry Number.
28484-87-9Relevant articles and documents
Inhibitors of Bacillus subtilis DNA polymerase III. 6-Anilinouracils and 6-(Alkylamino)uracils
Wright,Brown
, p. 34 - 38 (2007/10/02)
Substituted 6-anilinouracils were found to be potent inhibitors of the replication-specific enzyme, DNA polymerase III, from Bacillus subtilis. Inhibition potency was maximized by inclusion of small alkyl groups or halogens in the meta and para positions
