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6-(pentylamino)pyrimidine-2,4(1H,3H)-dione, also known as pentoxifylline, is a versatile chemical compound with a range of medicinal properties. It is primarily recognized as a vasodilator that enhances blood flow and circulation, making it a valuable treatment for conditions characterized by reduced blood flow. Pentoxifylline also exhibits anti-inflammatory and antioxidant effects, contributing to its efficacy in managing various medical conditions.

28484-87-9

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28484-87-9 Usage

Uses

Used in Cardiovascular Applications:
6-(pentylamino)pyrimidine-2,4(1H,3H)-dione is used as a vasodilator for improving blood flow and circulation, particularly in the treatment of intermittent claudication, a condition marked by leg pain and cramping due to insufficient blood flow.
Used in Peripheral Artery Disease Treatment:
In the medical industry, 6-(pentylamino)pyrimidine-2,4(1H,3H)-dione is utilized as a therapeutic agent for managing peripheral artery disease, leveraging its vasodilatory and anti-inflammatory properties to alleviate symptoms and improve patient outcomes.
Used in Diabetic Neuropathy Management:
6-(pentylamino)pyrimidine-2,4(1H,3H)-dione serves as a treatment for diabetic neuropathy, where its anti-inflammatory and antioxidant properties help to reduce inflammation and oxidative stress associated with this condition.
Used in Chronic Venous Insufficiency Therapy:
6-(pentylamino)pyrimidine-2,4(1H,3H)-dione is applied as a treatment for chronic venous insufficiency, using its ability to improve circulation and reduce inflammation in the affected veins.
Used in Sickle Cell Disease Symptom Reduction:
In the field of hematology, 6-(pentylamino)pyrimidine-2,4(1H,3H)-dione is investigated for its potential to alleviate symptoms of sickle cell disease, potentially improving the quality of life for patients suffering from this genetic disorder.
Used in Acute Pancreatitis Outcome Improvement:
6-(pentylamino)pyrimidine-2,4(1H,3H)-dione is also being studied for its role in improving outcomes in patients with acute pancreatitis, where its anti-inflammatory effects may contribute to better patient recovery.
Overall, 6-(pentylamino)pyrimidine-2,4(1H,3H)-dione, or pentoxifylline, has a diverse range of applications across various medical fields, and its potential continues to be explored for treating an array of conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 28484-87-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,4,8 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28484-87:
(7*2)+(6*8)+(5*4)+(4*8)+(3*4)+(2*8)+(1*7)=149
149 % 10 = 9
So 28484-87-9 is a valid CAS Registry Number.

28484-87-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(pentylamino)-1H-pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 6-pentylamino-1H-pyrimidine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28484-87-9 SDS

28484-87-9Downstream Products

28484-87-9Relevant academic research and scientific papers

Inhibitors of Bacillus subtilis DNA polymerase III. 6-Anilinouracils and 6-(Alkylamino)uracils

Wright,Brown

, p. 34 - 38 (2007/10/02)

Substituted 6-anilinouracils were found to be potent inhibitors of the replication-specific enzyme, DNA polymerase III, from Bacillus subtilis. Inhibition potency was maximized by inclusion of small alkyl groups or halogens in the meta and para positions

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