28485-24-7

Basic information

• Product Name: 1,5-dibenzylpyrimidine-2,4(1H,3H)-dione
• Synonyms: 2,4(1H,3H)-pyrimidinedione, 1,5-bis(phenylmethyl)-
• CAS NO: 28485-24-7
• Molecular Formula: C₁₈H₁₆N₂O₂
• Molecular Weight: 292.3318
• Mol File: 28485-24-7.mol
• Article Data: 2

Chemical Properties

• Density: 1.246g/cm³
• Refractive Index: 1.631
• CAS DataBase Reference: 1,5-dibenzylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-dibenzylpyrimidine-2,4(1H,3H)-dione(28485-24-7)
• EPA Substance Registry System: 1,5-dibenzylpyrimidine-2,4(1H,3H)-dione(28485-24-7)

Safety Data

• Hazardous Substances Data: 28485-24-7(Hazardous Substances Data)

Usage

Chemical structure

A pyrimidine derivative with two benzyl groups attached to the 1st and 5th positions, and a carbonyl group at the 2nd and 4th positions.

Appearance

Typically a solid or crystalline compound.

Biological activities

Exhibits antiviral and anticancer properties.

Organic synthesis

Used as a building block in the synthesis of various pharmacologically active compounds.

Pharmaceutical research

Investigated for its potential therapeutic applications in medicinal and pharmaceutical fields.

Solubility

Soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).

Stability

Generally stable under normal laboratory conditions, but sensitive to heat, light, and moisture.

Purity

Often synthesized with a high degree of purity for use in research and pharmaceutical applications.

Safety precautions

Handle with care, as it may have potential toxic effects. Use appropriate personal protective equipment (PPE) and follow proper disposal procedures.

Storage

Store in a cool, dry, and dark place, preferably in airtight containers to protect from light and moisture.

Upstream product

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• 943763-15-3 C₁₉H₂₃NO₃ 
• 868832-08-0 methyl 2-[(1-benzylureido)methyl]-3-phenylacrylate 
• 943763-33-5 ethyl 2-[(1-benzylureido)methyl]-3-phenylacrylate 
• 943763-21-1 ethyl 2-{[benzyl(cyano)amino]methyl}-3-hydroxy-3-phenylpropionate 
• 41244-53-5 5-bromo-2,4-bis(benzyloxy)pyrimidine 

Relevant articles and documents

Sodium hydride mediated cascade reaction towards the synthesis of 1,5-disubstituted uracil from cyanamides derived from Baylis-Hillman adducts

The substituted cyanamides generated from Baylis-Hillman adducts afford 1,5-disubstituted uracils via a sodium hydride induced cascade reaction involving sequential intramolecular attack of the hydroxy group on the nitrile group, cyclization of the result