28494-48-6

Usage

Uses

Used in Organic Synthesis:
4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE is used as a reagent for the synthesis of various organic compounds due to its reactivity and the presence of the nitro and carbohydrazide functional groups.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE serves as a building block for the preparation of pharmaceutical intermediates, contributing to the development of new drugs and therapeutic agents.
Used in Drug Development:
4-NITRO-1H-PYRROLE-2-CARBOHYDRAZIDE is utilized in drug development for its potential biological activities and pharmacological properties, which are being studied to explore its therapeutic applications and effects on various diseases and conditions.

InChI:InChI=1/C5H6N4O3/c6-8-5(10)4-1-3(2-7-4)9(11)12/h1-2,7H,6H2,(H,8,10)

Upstream product

• 53391-50-7 2,2,2-trichloro-1-(4-nitro-1H-pyrrol-2-yl)ethan-1-one 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 

Downstream Products

• 1616260-75-3 2-(4-nitro-1H-pyrrole-2-carbonyl)-N-phenylhydrazinecarboxamide 
• 1616260-76-4 N-(4-methoxyphenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarboxamide 
• 1616260-77-5 2-(4-nitro-1H-pyrrole-2-carbonyl)-N-(4-nitrophenyl)hydrazinecarboxamide 
• 1616260-78-6 N-(4-bromophenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarboxamide 
• 1616260-79-7 N-(4-chlorophenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarboxamide 
• 1616260-80-0 N-(2,5-dimethoxyphenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarboxamide 
• 1616260-81-1 N-benzyl-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarboxamide 
• 1616260-82-2 2-(4-nitro-1H-pyrrole-2-carbonyl)-N-phenethylhydrazinecarboxamide 
• 1616260-95-7 2-(4-nitro-1H-pyrrole-2-carbonyl)-N-(4-nitrophenyl)hydrazinecarbothioamide 
• 1616260-97-9 N-(4-fluorophenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarbothioamide 
• 1616260-99-1 N-(2-fluorophenyl)-2-(4-nitro-1H-pyrrole-2-carbonyl)hydrazinecarbothioamide 

Relevant academic research and scientific papers

Synthesis of novel 4-nitropyrrole-based semicarbazide and thiosemicarbazide hybrids with antimicrobial and anti-tubercular activity

We report the synthesis and screening of forty novel 4-nitropyrrole- semicarbazide conjugates inspired from the reported bio-potential of bromopyrrole alkaloids and semicarbazide derivatives for antimicrobial activity. Herein, hybrids 5k-5o, 5r, 5s and 5t

Synthesis of novel 4-nitropyrrole-based semicarbazide and thiosemicarbazide hybrids with antimicrobial and anti-tubercular activity

We report the synthesis and screening of forty novel 4-nitropyrrole-semicarbazide conjugates inspired from the reported bio-potential of bromopyrrole alkaloids and semicarbazide derivatives for antimicrobial activity. Herein, hybrids 5k-5o, 5r, 5s and 5t

Synthesis and evaluation of novel 4-nitropyrrole-based 1,3,4-oxadiazole derivatives as antimicrobial and anti-tubercular agents

We report synthesis and antimicrobial evaluation of 42 novel 4-nitropyrrole-based 1,3,4-oxadiazoles. The synthesized molecules were evaluated for anti-bacterial, anti-fungal and anti-tubercular activities. Promisingly, most of the compounds showed equal o