28507-02-0

Basic information

• Product Name: 16-bromoepiandrosterone
• Synonyms: 16-bromoepiandrosterone
• CAS NO: 28507-02-0
• Molecular Formula: C₁₉H₂₉BrO₂
• Molecular Weight: 369.33636
• Mol File: 28507-02-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 448.6°Cat760mmHg
• Flash Point: 225.1°C
• Appearance: /
• Density: 1.309g/cm³
• Vapor Pressure: 6.24E-10mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 16-bromoepiandrosterone(CAS DataBase Reference)
• NIST Chemistry Reference: 16-bromoepiandrosterone(28507-02-0)
• EPA Substance Registry System: 16-bromoepiandrosterone(28507-02-0)

Safety Data

• Hazardous Substances Data: 28507-02-0(Hazardous Substances Data)

Usage

General Description

16-bromoepiandrosterone is a synthetic derivative of the hormone epiandrosterone, which is a naturally occurring steroid hormone in the body. It is a brominated version of epiandrosterone and is commonly used as a prohormone or steroid alternative for various bodybuilding and athletic performance purposes. 16-bromoepiandrosterone is known for its ability to enhance muscle strength and growth, while also promoting fat loss and improving overall athletic performance. It is often taken as a supplement by bodybuilders and athletes looking to achieve lean muscle mass and improve their physical performance. However, its use and legality may vary depending on the country and governing sporting body regulations.

InChI:InChI=1/C19H29BrO2/c1-18-7-5-12(21)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(20)17(19)22/h11-16,21H,3-10H2,1-2H3/t11-,12-,13+,14-,15-,16+,18-,19-/m0/s1

Upstream product

• 481-29-8 Epiandrosterone 
• 53-43-0 dehydroepiandrosterone 
• 62675-96-1 16α-bromo-17,17-ethylendioxy-5α-androstan-3β-yl acetate 
• 3674-78-0 17,17-ethylendioxy-5α-androstan-3β-yl acetate 
• 1239-31-2 3β-acetoxy-5α-androstan-17-one 
• 18453-92-4 (3α,5β)-3-hydroxyandrostane-16,17-dione 16-oxime 
• 1242-55-3 3β-acetoxy-16α-bromo-5α-androstan-17-one 
• 18323-34-7 (3S,5S,8R,9S,10S,13S,14S)-16-Diazo-3-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-one 
• 5717-77-1 (3β,5α)-3-hydroxyandrostan-17-one, cyclic 1,2-ethanediyl acetal 

Downstream Products

• 1242-55-3 3β-acetoxy-16α-bromo-5α-androstan-17-one 
• 33386-51-5 3β-hydroxy-5α-androst-14-en-17-one 
• 1334215-26-7 16β-(1H-1,2,4-triazol-1-yl)-3β-piperidino-5α-androstan-17-one 
• 1332954-22-9 16β-(1H-benzimidazol-1-yl)-3β-(N-benzylmethylamino)-5α-androstan-17β-yl acetate 
• 1332954-21-8 16β-(1H-benzimidazol-1-yl)-3β-(N-methylphenylamino)-5α-androstan-17β-yl acetate 
• 1334215-15-4 16β-(1H-1,2,4-triazol-1-yl)-3β-pyrrolidino-5α-androstan-17-one 
• 1332954-20-7 16β-(1H-benzimidazol-1-yl)-3β-diethylamino-5α-androstan-17β-yl acetate 
• 1332954-19-4 16β-(1H-benzimidazol-1-yl)-3β-(4-methylpiperazinyl)-5α-androstan-17β-yl acetate 
• 1332954-18-3 16β-(1H-benzimidazol-1-yl)-3β-morpholino-5α-androstan-17β-yl acetate 

Relevant articles and documents

Preparation method of (3beta, 15alpha)-dihydroxyl-14beta-phenylamino or benzylaminoandrostane-17-ketone

The invention belongs to the field of chemical synthesis and relates to a preparation method of (3beta, 15alpha)-dihydroxyl-14beta-phenylamino or benzylaminoandrostane-17-ketone. The preparation method comprises the following steps of: utilizing natural steroid epiandrosterone as a raw material to react with copper bromide, then removing hydrogen bromide to obtain alkene, separating the obtained (3beta)-hydroxyl-androstane-14(15)-diene-17-ketone to react with MMPP, and obtaining an intermediate (3beta)-hydroxyl-14, 15-epoxy androstane-17-ketone; under the action of an acetic acid medium, usingphenylamine or benzylamine to carry out ring opening on epoxy units of the intermediate (3beta)-hydroxyl-14, 15-epoxy androstane-17-ketone, and obtaining a target compound. The product prepared by the invention has a carbonyl structure unit on a steroid rigid framework, and the structure units such as 14beta-NHPh or 14beta-NHCH2Ph and 15alpha-OH and the like play an important role in biological activity.

An efficient synthesis of 3β,14β-dihydroxy-5α-androst-15-en-17-one

An efficient four-step method has been developed for the synthesis of 3β,14β-dihydroxy-5α-androst-15-en-17-one from a common androstane derivative. The X-ray crystal structures of the alkenes, the epoxide and the 14-hydroxy compound have been determined.