285141-04-0Relevant articles and documents
A convenient dehydration procedure for the synthesis of enantiomerically pure cyanohydrins
Aquino, Fabrice,Pauling, Horst,Walther, Willy,Plattner, Dietmar A.,Bonrath, Werner
, p. 731 - 737 (2000)
Starting from protected α-hydroxy amides; cyanohydrins (α-hydroxy nitriles) are obtained through dehydration by cyanuric chloride/DMF in excellent yield. The advantages of the procedure are the extremely mild reaction conditions that prevent racemization.