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Di-o-tolyl-acetic acid, also known as 2,2'-oxybis(benzeneacetic acid) or 2,2'-dihydroxy-5,5'-dimethyldiphenylacetic acid, is an organic compound with the chemical formula C16H16O4. It is a white crystalline solid that is soluble in organic solvents and has a molecular weight of 276.30 g/mol. di-o-tolyl-acetic acid is characterized by two phenyl rings, each bearing a methyl group (-CH3) at the ortho position (the position adjacent to the hydroxyl group) and a carboxylic acid group (-COOH) at the para position. Di-o-tolyl-acetic acid is used in the synthesis of various pharmaceuticals and chemical intermediates, particularly in the production of nonsteroidal anti-inflammatory drugs (NSAIDs) and other medicinal compounds. Its chemical structure and properties make it a versatile building block in organic chemistry and drug development.

2852-67-7

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2852-67-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2852-67-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,5 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2852-67:
(6*2)+(5*8)+(4*5)+(3*2)+(2*6)+(1*7)=97
97 % 10 = 7
So 2852-67-7 is a valid CAS Registry Number.

2852-67-7Downstream Products

2852-67-7Relevant academic research and scientific papers

A Study of the Ferrous Ion-initiated SRN1 Reactions of Halogenoarenes with tert-Butyl Acetate and N-Acylmorpholine Enolates

Leeuwen, Milko van,McKillop, Alexander

, p. 2433 - 2440 (2007/10/02)

A detailed preparative study is reported of the ferrous ion-initiated SRN1 reactions of a range of halogenoarenes with the sodium enolates of tert-butyl acetate, n-acetylmorpholine and a number of higher N-acylmorpholines.Smooth and rapid substitution occurs in many cases, and good to excellent yields were obtained of arylacetic esters or acids, arylacetamides and arylalkanamides.The broad scope and limitations of the process have been defined, and the possible role of the ferrous ion is discussed.

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