28531-05-7

Upstream product

• 2786-07-4 2-thienyl lithium 
• 17583-40-3 2-methylaminobenzonitrile 
• 4075-59-6 2-thiopheneglyoxylic acid 
• 100-61-8 N-methylaniline 

Downstream Products

• 1610460-80-4 3-benzyl-1-methyl-3-(thiophen-2-yl)indolin-2-one 
• 154010-85-2 o-phenyl 2-thienyl ketone 

Relevant academic research and scientific papers

Synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by: Tert -butyl nitrite

In this paper, a regioselective, efficient and convenient synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by tert-butyl nitrite is presented. Interestingly, tert-butyl nitrite acts as not only an efficient and mild nitrosation reagent, but also a sustainable oxidant required in the Pd(ii)-catalyzed decarboxylative acylation. Meanwhile, the NO unit turned out to be an easily introduced and readily removable directing group for the regioselective acylation.

Method for synthesizing 2-aminobenzophenone compound

The invention discloses a method for synthesizing a 2-aminobenzophenone compound, and belongs to the technical field of organic synthesis. According to the key point of the technical scheme, the method comprises the following steps that an N-nitroso-2-ami

An Expeditious Synthesis of 3-Alkyl-, Aryl- and Heteroaryl-indoles by way of an Intramolecular Horner-Wittig Reaction

A variety of 3-alkyl-, aryl- and heteroaryl-indoles have been efficiently prepared by base-induced intramolecular cyclization of suitable aromatic o-acyl substituted Horner-Wittig reagents.