28558-66-9

Basic information

• Product Name: 4-{[(E)-(1-benzyl-1H-indol-3-yl)methylidene]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide
• CAS NO: 28558-66-9
• Molecular Formula: C₂₅H₂₀N₄O₂S₂
• Molecular Weight: 472.5819
• Mol File: 28558-66-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 719.6°C at 760 mmHg
• Flash Point: 389°C
• Density: 1.34g/cm³
• Vapor Pressure: 1.47E-20mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 4-{[(E)-(1-benzyl-1H-indol-3-yl)methylidene]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(E)-(1-benzyl-1H-indol-3-yl)methylidene]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide(28558-66-9)
• EPA Substance Registry System: 4-{[(E)-(1-benzyl-1H-indol-3-yl)methylidene]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide(28558-66-9)

Safety Data

• Hazardous Substances Data: 28558-66-9(Hazardous Substances Data)

Usage

General Description

This chemical, also known as Bz-423, is a synthetic compound designed as a potential anti-inflammatory and anti-cancer agent. It contains a benzylindole and a thiazole group, both of which are known for their biological activities. The compound is a sulfonamide derivative with a methylideneamino group, and it has been studied for its potential to inhibit the activity of a protein called NEMO, which is involved in regulating the body's inflammatory response. Research has shown that Bz-423 has promising anti-inflammatory and anti-cancer properties, making it a potential candidate for further drug development.

Upstream product

• 72-14-0 Sulfathiazole 
• 10511-51-0 1-Benzylindole-3-carboxaldehyde